The bottom‐up construction of a synthetic cell from nonliving building blocks capable of
mimicking cellular properties and behaviors helps to understand the particular biophysical …

Compartmentalization of biological content and function is a key architectural feature in
biology, where membrane bound micro-and nanocompartments are used for performing a …

Constructing higher-order vesicle assemblies has discipline-spanning potential from
responsive soft-matter materials to artificial cell networks in synthetic biology. This potential …

In nature, cells self-assemble into spatially coded tissular configurations to execute higher-
order biological functions as a collective. This mechanism has stimulated the recent trend in …

The design of membrane-based constructs with multiple compartments is of increasing
importance given their potential applications as microreactors, as artificial cells in synthetic …

Membrane fusion processes play key roles in biological transformations, such as
endocytosis/exocytosis, signal transduction, neurotransmission, or viral infections, and …

The use of artificial cells to mimic living tissues is beneficial for understanding the
mechanism of interaction among cells. Artificial cells hold immense potential in the field of …

Highlights•The bottom-up reconstitution of biological systems will give new insights into the
mechanisms and origin of life.•Cutting-edge biotechnological tools and methods facilitate …

DNA nanotechnology allows for the design of programmable DNA-built nanodevices which
controllably interact with biological membranes and even mimic the function of natural …

The interplay between nucleic acids and lipids underpins several key processes in
molecular biology, synthetic biotechnology, vaccine technology, and nanomedicine. These …