In human beings the immature brain is highly plastic and depending on the stage of
gestation is particularly vulnerable to a range of insults that if sufficiently severe, can result in …

Neonates can develop hypoxic-ischaemic encephalopathy (HIE) due to lack of blood supply
or oxygen, resulting in a major cause of death and disability among term newborns …

Importance Neonatal hypoxic-ischemic encephalopathy (HIE) remains a significant cause of
neurologic disability. Identifying infants suitable for therapeutic hypothermia (TH) within a …

Placental and fetal hypoxia caused by perinatal hypoxic-ischemic events are major causes
of stillbirth, neonatal morbidity, and long-term neurological sequelae among surviving …

Introduction: Neonatal hypoxic-ischemic brain injury (HIBI) results in significant morbidity
and mortality despite current available therapies. Seeking a potential supplemental therapy …

Introduction: Perinatal asphyxia is a leading cause of neonatal death. Up to one-third of
asphyxiated neonates suffer from hypoxic-ischaemic encephalopathy (HIE) with substantial …

Neonatal hypoxic–ischemic brain injury (HIBI) is a devastating injury resulting from impaired
blood flow and oxygen delivery to the brain at or around the time of birth. Despite the use of …

Hypoxic ischemic encephalopathy (HIE) is the most frequent cause of acquired infant brain
injury. Early, clinically relevant biomarkers are required to allow timely application of …

Circular RNA (circRNA) is a newly discovered noncoding RNA that regulates gene
transcription, binds to RNA-related proteins, and encodes protein microRNAs (miRNAs). The …

Hypoxic-ischemic (HI) brain injury is a leading cause of acute mortality and chronic disability
in newborns. Current evidence shows that cerebral microvascular response and …