Hepatocellular carcinoma (HCC) is the third leading cause of cancer-related deaths
worldwide. Only 30%-40% of the patients with HCC are eligible for curative treatments …

Hox genes encode a family of transcriptional regulators that elicit distinct developmental
programmes along the head-to-tail axis of animals. The specific regional functions of …

Simple Summary Hepatocellular carcinoma (HCC) is one of the most frequently occurring
cancers, and the prognosis for late-stage HCC remains poor. A better understanding of the …

Hepatocellular carcinoma (HCC) is one of the most common types of malignancies
worldwide. There is little information on the mechanisms involved in the pathogenesis of this …

High mobility group box 1 (HMGB1) is an extremely versatile protein that is located
predominantly in the nucleus of quiescent eukaryotic cells, where it is critically involved in …

CircRNAs (circular RNAs), recently identified as a critical regulator in tumorigenesis,
participate in CRC (colorectal cancer) growth. However, the role of hsa_circRNA_002144 in …

Hepatocellular carcinoma (HCC) is the third leading cause of cancer deaths worldwide.
Despite improvements in HCC therapy, the prognosis for HCC patients remains poor due to …

The insulin family consists of insulin, insulin-like growth factor 1 (IGF-1), insulin-like growth
factor 2 (IGF-2), their receptors (IR, IGF-1R and IGF-2R), and their binding proteins. All three …

The insulin-like growth factor (IGF)-axis has been paradigmatically involved in
hepatocellular carcinoma (HCC) tumor initiation, progression and drug resistance …

Hepatocellular carcinoma (HCC) is one of the most common cancers worldwide and the
third cause of cancer‐related death. Poor understanding of the mechanisms underlying the …