Melatonin was found to be a potent free radical scavenger in 1993. Since then over 800
publications have directly or indirectly confirmed this observation. Melatonin scavenges a …

The gastrointestinal tract of vertebrate species is a rich source of extrapineal melatonin. The
concentration of melatonin in the gastrointestinal tissues surpasses blood levels by 10–100 …

Gut health is important for nutrition absorption, reproduction, and lactation in perinatal and
early weaned mammals. Although melatonin functions in maintaining circadian rhythms and …

Preeclampsia remains a leading cause of maternal and perinatal morbidity and mortality.
There have been no material advances in the treatment of preeclampsia for nearly 50 years …

Oxidative response and inflammation constitute a major defense against infections, but if not
properly regulated they could also lead to a number of deleterious effects. Patients affected …

Melatonin is now known to be a multifaceted free radical scavenger and antioxidant. It
detoxifies a variety of free radicals and reactive oxygen intermediates including the hydroxyl …

The pharmacological effects of melatonin, vitamin E, vitamin C, glutathione and
desferrioxamine (desferoxamine) alone and in combination on iron‐induced membrane lipid …

Bile is an important physiological bodily fluid which functions in the regulation of cholesterol
metabolism, promotes the absorption of lipid and fat-soluble vitamins by the gut and serves …

This review briefly summarizes the actions of melatonin in reducing molecular damage
caused by free radicals and associated oxygen-and nitrogenbased reactants. All the …

Melatonin (MT) is secreted primarily by the pineal gland in response to environmental
light/dark cycles which are produced by supra-chiasmatic nuclei (SCN), the major circadian …