The periodontal complex involves the hard and soft tissues which support dentition,
comprised of cementum, bone, and the periodontal ligament (PDL). Periodontitis, a …

This year marks the tenth anniversary of the world's first transplantation of tissue generated
from induced pluripotent stem cells (iPSCs). There is now a growing number of clinical trials …

Purpose The anticipated emergence of hemophilia gene therapy will present people with
hemophilia (PWH) and treating clinicians with increasingly complex treatment options. It will …

Importance In addition to technical barriers, public attitudes about the use of gene therapy
have an important association with the clinical implementation of gene therapy. Objective To …

Many gene therapies are in development for treating people with inherited retinal diseases
(IRD). We hypothesized that potential recipients of gene therapy would have knowledge …

Abstract Coronavirus 2019 (COVID-19) has caused significant disruption to the cell and
gene therapy (CGT) industry, which has historically faced substantial complexities in supply …

Little is known about patients' and families' lived experiences of participating in pediatric
gene therapy (GT) clinical trials. Currently, pediatric GT research targets a broad range of …

Background The electrical cochlear implant (eCI) partially restores hearing in individuals
affected by profound hearing impairment (HI) or deafness. However, the limited resolution of …

In clinical medicine, shared decision making (SDM) is a well-recognized strategy to enhance
engagement of both patients and clinicians in medical decisions. The success of liver …

Translational medicine, an interdisciplinary branch of biomedical research, aims to rapidly
transform scientific discoveries into interventions for testing in clinical settings and adoption …