Endothelial dysfunction over the course of coronary artery disease

E Gutierrez, AJ Flammer, LO Lerman… - European heart …, 2013 - academic.oup.com
The vascular endothelium regulates blood flow in response to physiological needs.
Endothelial dysfunction is closely related to atherosclerosis and its risk factors, and it …

Current status of bioresorbable scaffolds in the treatment of coronary artery disease

J Wiebe, HM Nef, CW Hamm - Journal of the American College of …, 2014 - jacc.org
State-of-the-art drug-eluting metal stents are the gold standard for interventional treatment of
coronary artery disease. Although they overcome some disadvantages and limitations of …

Everolimus-eluting bioresorbable stent vs. durable polymer everolimus-eluting metallic stent in patients with ST-segment elevation myocardial infarction: results of the …

M Sabaté, S Windecker, A Iñiguez… - European heart …, 2016 - academic.oup.com
Aims Patients with ST-segment elevation myocardial infarction (STEMI) feature thrombus-
rich lesions with large necrotic core, which are usually associated with delayed arterial …

Bioresorbable scaffolds: rationale, current status, challenges, and future

J Iqbal, Y Onuma, J Ormiston, A Abizaid… - European heart …, 2014 - academic.oup.com
Current generation of drug-eluting stents has significantly improved the outcomes of
percutaneous coronary intervention by substantially reducing in-stent restenosis and stent …

Very late scaffold thrombosis: intracoronary imaging and histopathological and spectroscopic findings

L Räber, S Brugaletta, K Yamaji, CJ O'Sullivan… - Journal of the American …, 2015 - jacc.org
Background: Bioresorbable scaffolds provide transient lumen support followed by complete
resorption. Objectives: This study examined whether very late scaffold thrombosis (VLScT) …

Scaffold thrombosis after percutaneous coronary intervention with ABSORB bioresorbable vascular scaffold: a systematic review and meta-analysis

MJ Lipinski, RO Escarcega, NC Baker, HA Benn… - JACC: Cardiovascular …, 2016 - jacc.org
Objectives: The aim of this study was to determine the risk of scaffold thrombosis (ST) after
percutaneous coronary intervention (PCI) with placement of an ABSORB bioresorbable …

Chronic rapamycin restores brain vascular integrity and function through NO synthase activation and improves memory in symptomatic mice modeling Alzheimer's …

AL Lin, W Zheng, JJ Halloran… - Journal of Cerebral …, 2013 - journals.sagepub.com
Vascular pathology is a major feature of Alzheimer's disease (AD) and other dementias. We
recently showed that chronic administration of the target-of-rapamycin (TOR) inhibitor …

Stent thrombosis with drug-eluting stents and bioresorbable scaffolds: evidence from a network meta-analysis of 147 trials

SH Kang, IH Chae, JJ Park, HS Lee, DY Kang… - Cardiovascular …, 2016 - jacc.org
Objectives This study sought to perform a systematic review and network meta-analysis to
compare the relative safety and efficacy of contemporary DES and BVS. Background To …

[HTML][HTML] Understanding the impact of stent and scaffold material and strut design on coronary artery thrombosis from the basic and clinical points of view

A Sakamoto, H Jinnouchi, S Torii, R Virmani, AV Finn - Bioengineering, 2018 - mdpi.com
The technology of percutaneous coronary intervention (PCI) is constantly being refined in
order to overcome the shortcomings of present day technologies. Even though current …

Bioresorbable vascular scaffolds—basic concepts and clinical outcome

C Indolfi, S De Rosa, A Colombo - Nature Reviews Cardiology, 2016 - nature.com
The introduction of percutaneous treatment of coronary artery stenosis with balloon
angioplasty was the first revolution in interventional cardiology; the advent of metallic …