Vaccines have had a profound impact on the management and prevention of infectious
disease. In addition, the development of vaccines against chronic diseases has attracted …

Treatment options for patients with HER2-positive advanced gastric cancer are limited, and
the prognosis for these patients is poor. Pembrolizumab has demonstrated promising …

Several therapeutic monoclonal antibodies (mAbs), including those targeting epidermal
growth factor receptor, human epidermal growth factor receptor 2 (HER2), and CD20 …

Introduction Immune checkpoint inhibitor (ICI) monotherapy appears to be effective in a
small cohort of patients with metastatic triple negative breast cancer (mTNBC). This supports …

Despite being a standard treatment option in breast cancer, immune checkpoint inhibitors
(ICIs) are only efficacious for a subset of patients. To gain a better understanding of the …

This review discusses peptide epitopes used as antigens in the development of vaccines in
clinical trials as well as future vaccine candidates. It covers peptides used in potential …

Breast Cancer (BC) is the second most frequent cause of cancer death among women
worldwide and, although there have been significant advances in BC therapies, a significant …

In recent years, the tumor microenvironment (TME) has been a research hotspot, as it is
composed of distinct cellular and non-cellular elements that may influence the diagnosis …

Overexpression of human epidermal growth factor receptor 2 (HER2) occurs in
approximately 15–20% of breast cancer cases. HER2 is a member of the epidermal growth …

Simple Summary To date, different therapeutic strategies, including immunotherapies, have
been shown to prolong survival in breast cancer patients, representing one of the most …