Exosomes are nano-sized vesicles that serve as mediators for cell-to-cell communication.
With their unique nucleic acids, proteins, and lipids cargo compositions that reflect the …

The cells secrete extracellular vesicles (EV) that may have an endosomal origin, or from
evaginations of the plasma membrane. The former are usually called exosomes, with sizes …

Cellular senescence is a persistently hypoproliferative state with diverse stressors in a
specific aging microenvironment. Senescent cells have a double‐edged sword effect: they …

Blood–brain barrier (BBB) breakdown after ischemic stroke exacerbates brain injury and
BBB senescence can cause severe neurological deficits in aged ischemic stroke population …

Stem cell derived small extracellular vesicles (sEVs) have been proved to promote
neurological recovery after stroke. Recent studies demonstrate a phenomenal tissue repair …

Stem cell senescence increases alongside the progressive functional declines that
characterize aging. The effects of extracellular vesicles (EVs) are now attracting intense …

Simple Summary Aging and frailty are complex processes implicating multifactorial
mechanisms, which demand for new therapeutic strategies against their devastating effects …

Ageing induces a great risk factor that participates in progressing various degenerative
diseases morbidities. The main characteristic of ageing is the failure in maintaining …

Extracellular vesicles (EVs) are cell-derived biological nanoparticles that gained great
interest for drug delivery. EVs have numerous advantages compared to synthetic …

In the last few decades, the practical use of stem cells (SCs) in the clinic has attracted
significant attention in the regenerative medicine due to the ability of these cells to proliferate …