Inflammation and oxidative stress in snakebite envenomation: a brief descriptive review and clinical implications
D Resiere, H Mehdaoui, R Neviere - Toxins, 2022 - mdpi.com
Snakebite envenoming is a pathological condition which may occur in response to the
injection of venom. Snake venoms contain a complex mixture of biologically active …
injection of venom. Snake venoms contain a complex mixture of biologically active …
[HTML][HTML] Polymorphonuclear neutrophil leukocytes in snakebite envenoming
Polymorphonuclear neutrophils are the most abundant leukocytes in the blood and
constitute key components of the innate immunity. Upon infection or tissue damage …
constitute key components of the innate immunity. Upon infection or tissue damage …
Biogeographic venom variation in Russell's viper (Daboia russelii) and the preclinical inefficacy of antivenom therapy in snakebite hotspots
RR Senji Laxme, S Khochare, S Attarde… - PLoS neglected …, 2021 - journals.plos.org
Background Snakebite in India results in over 58,000 fatalities and a vast number of
morbidities annually. The majority of these clinically severe envenomings are attributed to …
morbidities annually. The majority of these clinically severe envenomings are attributed to …
Biogeographical venom variation in the Indian spectacled cobra (Naja naja) underscores the pressing need for pan-India efficacious snakebite therapy
RR Senji Laxme, S Attarde, S Khochare… - PLOS neglected …, 2021 - journals.plos.org
Background Snake venom composition is dictated by various ecological and environmental
factors, and can exhibit dramatic variation across geographically disparate populations of …
factors, and can exhibit dramatic variation across geographically disparate populations of …
Fangs in the Ghats: preclinical insights into the medical importance of pit vipers from the Western Ghats
S Khochare, RR Senji Laxme, P Jaikumar… - International Journal of …, 2023 - mdpi.com
The socioeconomic impact of snakebites in India is largely attributed to a subset of snake
species commonly known as the 'big four'. However, envenoming by a range of other …
species commonly known as the 'big four'. However, envenoming by a range of other …
Remarkable intrapopulation venom variability in the monocellate cobra (Naja kaouthia) unveils neglected aspects of India's snakebite problem
Interpopulation venom variation has been widely documented in snakes across large
geographical distances. This variability is known to markedly influence the effectiveness of …
geographical distances. This variability is known to markedly influence the effectiveness of …
Diacetoxyscirpenol-induced heterophil extracellular traps contribute to the immune toxicity of liver injury in chickens
D Wu, S Li, P Li, A Jiang, Z Liu, Y Zhang, J Wang… - Food and Chemical …, 2021 - Elsevier
Diacetoxyscirpenol (DAS) is one kind of type A trichothecene mycotoxin which produced by
Fusarium species which contaminates agricultural crops and food. DAS attracts particular …
Fusarium species which contaminates agricultural crops and food. DAS attracts particular …
Targeting Neutrophil Extracellular Traps in Gouty Arthritis: Insights into Pathogenesis and Therapeutic Potential
C Li, C Wu, F Li, W Xu, X Zhang… - Journal of Inflammation …, 2024 - Taylor & Francis
Gouty arthritis (GA) is an immune-mediated disorder characterized by severe inflammation
due to the deposition of monosodium urate (MSU) crystals in the joints. The …
due to the deposition of monosodium urate (MSU) crystals in the joints. The …
Toxoplasma gondii triggers heterophil extracellular traps via NADPH oxidase, ERK1/2 and P38 signalling pathways, glycolysis and autophagy in chickens
M Chen, Z Jin, Q Jin, W Liu, X Gao, H Hong… - Parasite …, 2023 - Wiley Online Library
Toxoplasma gondii is a zoonotic parasite with a global distribution. Heterophil extracellular
traps (HETs) are a novel innate immune mechanism of chickens against pathogens, but …
traps (HETs) are a novel innate immune mechanism of chickens against pathogens, but …
[HTML][HTML] Effects of venoms on neutrophil respiratory burst: a major inflammatory function
J El-Benna, M Hurtado-Nedelec… - Journal of Venomous …, 2021 - SciELO Brasil
Neutrophils play a pivotal role in innate immunity and in the inflammatory response.
Neutrophils are very motile cells that are rapidly recruited to the inflammatory site as the …
Neutrophils are very motile cells that are rapidly recruited to the inflammatory site as the …