Established and emerging players in phospholipid scrambling: a structural perspective
The maintenance of a diverse and non-homogeneous lipid composition in cell membranes
is crucial for a multitude of cellular processes. One important example is transbilayer lipid …
is crucial for a multitude of cellular processes. One important example is transbilayer lipid …
A cholesterol switch controls phospholipid scrambling by G protein–coupled receptors
Class AG protein-coupled receptors (GPCRs), a superfamily of cell membrane signaling
receptors, moonlight as constitutively active phospholipid scramblases. The plasma …
receptors, moonlight as constitutively active phospholipid scramblases. The plasma …
Exploring Mutation-Driven Changes in the ATP-ADP Conformational Cycle of Human Hsp70 by All-Atom MD Adaptive Sampling
Hsp70 belongs to a family of molecular chaperones ubiquitous through organisms that
assist client protein folding and prevent aggregation. It works through a tightly ATP-regulated …
assist client protein folding and prevent aggregation. It works through a tightly ATP-regulated …
[HTML][HTML] Environmental triggers and future risk of developing autoimmune diseases: Molecular mechanism and network toxicology analysis of bisphenol A
Y Hong, D Wang, Y Lin, Q Yang, Y Wang, Y Xie… - Ecotoxicology and …, 2024 - Elsevier
Bisphenol A (BPA), a chemical compound in plastics and resins, widely exist in people's
production and life which have great potential to damage human and animal health. It has …
production and life which have great potential to damage human and animal health. It has …
Online Boosted Gaussian Learners for In-Situ Detection and Characterization of Protein Folding States in Molecular Dynamics Simulations
Molecular Dynamics (MD) simulations are a crucial tool for understanding how proteins fold.
In its easiest form, MD simulations can be scaled through data parallelism, this means that …
In its easiest form, MD simulations can be scaled through data parallelism, this means that …
Human class B1 GPCR modulation by plasma membrane lipids
The class B1 G protein-coupled receptor (GPCR) subfamily is a class of receptors known for
their regulatory roles in metabolism and neuronal activity important as drug targets. Lipids …
their regulatory roles in metabolism and neuronal activity important as drug targets. Lipids …