Antibiotic resistance in bacterial pathogens presents a substantial threat to the control of
infectious diseases. Development of new classes of antibiotics has slowed in recent years …

Strictly lytic phages have been consensually preferred for phage therapy purposes. In
contrast, temperate phages have been avoided due to an inherent capacity to mediate …

The current problems with increasing bacterial resistance to antibacterial therapies, resulting
in a growing frequency of incurable bacterial infections, necessitates the acceleration of …

Soon after their discovery in the early 20th century, bacteriophages were recognized to have
great potential as antimicrobial agents, a potential that has yet to be fully realized. The …

The emergence and spread of antibiotic-resistant bacteria drives the search for novel
classes of antibiotics to replenish our armamentarium against bacterial infections. This is …

Antibiotic resistance ranks among the top threats to humanity. Due to the frequent use of
antibiotics, society is facing a high prevalence of multidrug resistant pathogens, which have …

Despite advances in modern technologies, various foodborne outbreaks have continuously
threatened the food safety. The overuse of and abuse/misuse of antibiotics have escalated …

Genome engineering of bacteriophages provides opportunities for precise genetic
dissection and for numerous phage applications including therapy. However, few methods …

Phage therapy represents a possible treatment option to cure infections caused by multidrug-
resistant bacteria, including methicillin and vancomycin-resistant Staphylococcus aureus, to …

Concerns over drug-resistant bacteria have stimulated interest in developing alternative
methods to control bacterial infections. Endolysin, a phage-encoded enzyme that breaks …