The introduction of technologies such as mass spectrometry and protein and DNA arrays,
combined with our understanding of the human genome, has enabled simultaneous …

The focus of this article is to review the recent advances in proteome analysis of human
body fluids, including plasma/serum, urine, cerebrospinal fluid, saliva, bronchoalveolar …

Background: Protein expression profiling for differences indicative of early cancer has
promise for improving diagnostics. This report describes the first stage of a National Cancer …

Head and neck squamous cell carcinoma (HNSCC) involves the upper aerodigestive tract
and can destroy the structure and function of organs involved in voice, speech, taste, smell …

In this article, we present an overview of the different strategies for sample preparation for
identification by mass spectrometry (MS) of biomarkers from serum and/or plasma. We …

Purpose: To evaluate aberrant promoter hypermethylation of candidate tumor suppressor
genes as a means to detect epigenetic alterations specific to solid tumors, including head …

Recently, the focus of cancer research has expanded from genetic information in the human
genome to protein expression analyses. Because this 'proteome'reflects the state of a cell …

Head and neck squamous cell carcinoma (HNSCC), as a complex and variable malignancy,
poses a significant threat to human health. Since the intricate association between HPV and …

Purpose: We recently showed that protein expression profiling of serum using surface-
enhanced laser desorption/ionization time-of-flight mass spectrometry (SELDI-TOF MS) has …

Background: This report presents updated National Academy of Clinical Biochemistry
Laboratory Medicine Practice Guidelines summarizing quality requirements for the use of …