Lipids are essential metabolites, which function as energy sources, structural components
and signalling mediators. Most cells are able to convert carbohydrates into fatty acids, which …

Cellular lipid metabolism and homeostasis are controlled by sterol regulatory-element
binding proteins (SREBPs). In addition to performing canonical functions in the …

During the recent decades, awareness towards the role of essential fatty acids in human
health and disease prevention has been unremittingly increasing among people. Fish, fish …

Polyunsaturated fatty acids (PUFAs) can be classified in n− 3 fatty acids and n− 6 fatty acids,
and in westernized diet the predominant dietary PUFAs are n− 6 fatty acids. Both types of …

Since the pathways of glycerolipid biosynthesis were elucidated in the 1950's, considerable
knowledge has been gained about the enzymes that catalyze the lipid biosynthetic reactions …

This review focuses on the metabolism of n-3 fatty acids and attempts to review the current
understanding of how the n-3 fatty acid content of neuronal membranes is regulated …

De novo lipogenesis (DNL) is a complex yet highly regulated metabolic pathway, and
transcription factors such as liver X receptor (LXR), sterol regulatory element-binding protein …

Abstract High-fat (HF)-diet rodent models have contributed significantly to the analysis of the
pathophysiology of the insulin resistance syndrome, but their phenotype varies distinctly …

Oxygenated derivatives of cholesterol (oxysterols) present a remarkably diverse profile of
biological activities, including effects on sphingolipid metabolism, platelet aggregation …

Roles of sterol regulatory element-binding proteins (SREBPs) have been established as
lipid synthetic transcription factors especially for cholesterol and fatty acid synthesis …