Since their discovery in the 1980s and 1990s, the human protein lysine acetyltransferase
encoded by the paralogous p300 and CBP genes has received much interest. p300/CBP …

Significance: Oxidative stress, an excess of reactive oxygen species (ROS) production
versus consumption, may be involved in the pathogenesis of different diseases. The only …

Breast cancer is the most common form of cancer diagnosed in women worldwide and the
second leading cause of cancer-related deaths in the USA. Despite the development of …

Purpose Reactive oxygen species (ROS) are produced in cancer cells as a result of
increased metabolic rate, dysfunction of mitochondria, elevated cell signaling, expression of …

Antimicrobial resistance (AMR) is a global problem hindering treatment of bacterial
infections, rendering many aspects of modern medicine less effective. AMR genes (ARGs) …

Epithelial-to-mesenchymal transition (EMT) is a self-regulated physiological process
required for tissue repair that, in non-controled conditions may lead to fibrosis …

Human skin, eye and hair color rely on the production of melanin, depending on its quantity,
quality, and distribution, Melanin plays a monumental role in protecting the skin against the …

One of the leading global causes of death is cancer; even though several treatment methods
have improved survival rates, the incidence and fatality rates remain high. Naphthoquinones …

Standard anti-cancer therapies promote tumor growth suppression mainly via induction of
apoptosis. However, in most cases cancer cells acquire the ability to escape apoptotic cell …

Hepatocellular carcinoma (HCC), the most common type of primary liver cancer, remains a
global health challenge requiring novel and effective therapeutic agents and approaches …