m6A in mRNA: an ancient mechanism for fine-tuning gene expression
JY Roignant, M Soller - Trends in Genetics, 2017 - cell.com
Modifications in mRNA constitute ancient mechanisms to regulate gene expression post-
transcriptionally. N 6-methyladenosine (m 6 A) is the most prominent mRNA modification …
transcriptionally. N 6-methyladenosine (m 6 A) is the most prominent mRNA modification …
[HTML][HTML] Non-coding RNAs: multi-tasking molecules in the cell
In the last years it has become increasingly clear that the mammalian transcriptome is highly
complex and includes a large number of small non-coding RNAs (sncRNAs) and long …
complex and includes a large number of small non-coding RNAs (sncRNAs) and long …
RP5-833A20. 1/miR-382-5p/NFIA–dependent signal transduction pathway contributes to the regulation of cholesterol homeostasis and inflammatory reaction
YW Hu, JY Zhao, SF Li, JL Huang, YR Qiu… - … , and vascular biology, 2015 - Am Heart Assoc
Objective—Cardiovascular disease caused by atherosclerosis is the number one cause of
death in Western countries and threatens to become the major cause of morbidity and …
death in Western countries and threatens to become the major cause of morbidity and …
Stress-activated miR-21/miR-21* in hepatocytes promotes lipid and glucose metabolic disorders associated with high-fat diet consumption
N Calo, P Ramadori, C Sobolewski, Y Romero… - Gut, 2016 - gut.bmj.com
Objective miR-21 is an oncomir highly upregulated in hepatocellular carcinoma and in early
stages of liver diseases characterised by the presence of steatosis. Whether upregulation of …
stages of liver diseases characterised by the presence of steatosis. Whether upregulation of …
Use of Tripterygium wilfordii Hook F for immune-mediated inflammatory diseases: progress and future prospects
C Song, Y Xu, Y Lu - Journal of Zhejiang University-Science B, 2020 - Springer
Tripterygium wilfordii Hook F has significant anti-inflammatory and immunosuppressive
properties and is widely used for treating autoimmune and inflammatory diseases such as …
properties and is widely used for treating autoimmune and inflammatory diseases such as …
miR-23a is decreased during muscle atrophy by a mechanism that includes calcineurin signaling and exosome-mediated export
MB Hudson, ME Woodworth-Hobbs… - … of Physiology-Cell …, 2014 - journals.physiology.org
Skeletal muscle atrophy is prevalent in chronic diseases, and microRNAs (miRs) may play a
key role in the wasting process. miR-23a was previously shown to inhibit the expression of …
key role in the wasting process. miR-23a was previously shown to inhibit the expression of …
[HTML][HTML] Cardiovascular microRNAs: as modulators and diagnostic biomarkers of diabetic heart disease
Diabetic heart disease (DHD) is the leading cause of morbidity and mortality among the
people with diabetes, with approximately 80% of the deaths in diabetics are due to …
people with diabetes, with approximately 80% of the deaths in diabetics are due to …
C/D‐box snoRNAs form methylating and non‐methylating ribonucleoprotein complexes: Old dogs show new tricks
M Falaleeva, JR Welden, MJ Duncan, S Stamm - Bioessays, 2017 - Wiley Online Library
C/D box snoRNAs (SNORDs) are an abundantly expressed class of short, non‐coding
RNAs that have been long known to perform 2′‐O‐methylation of rRNAs. However …
RNAs that have been long known to perform 2′‐O‐methylation of rRNAs. However …
[HTML][HTML] Metabolic characterization of cell systems used in in vitro toxicology testing: lung cell system BEAS-2B as a working example
C Garcia-Canton, E Minet, A Anadon, C Meredith - Toxicology in Vitro, 2013 - Elsevier
The bioactivation of pro-toxicants is the biological process through which some chemicals
are metabolized into reactive metabolites. Therefore, in vitro toxicological evaluation should …
are metabolized into reactive metabolites. Therefore, in vitro toxicological evaluation should …
[HTML][HTML] MiR-200c and HuR in ovarian cancer
S Prislei, E Martinelli, M Mariani, G Raspaglio, S Sieber… - BMC cancer, 2013 - Springer
Background MicroRNAs in solid malignancies can behave as predictors of either good or
poor outcome. This is the case with members of the miR-200 family, which are the primary …
poor outcome. This is the case with members of the miR-200 family, which are the primary …