[HTML][HTML] Mechanisms of immunothrombosis and vasculopathy in antiphospholipid syndrome

JS Knight, Y Kanthi - Seminars in immunopathology, 2022 - Springer
Antiphospholipid syndrome (APS) is an autoimmune thrombophilia propelled by circulating
antiphospholipid antibodies that herald vascular thrombosis and obstetrical complications …

Antiphospholipid syndrome

K Schreiber, S Sciascia, PG De Groot… - Nature reviews Disease …, 2018 - nature.com
Antiphospholipid syndrome (APS) is an autoimmune disease characterized by the presence
of antiphospholipid antibodies, such as lupus anticoagulant, anticardiolipin antibodies and …

Release of neutrophil extracellular traps by neutrophils stimulated with antiphospholipid antibodies: a newly identified mechanism of thrombosis in the …

S Yalavarthi, TJ Gould, AN Rao, LF Mazza… - Arthritis & …, 2015 - Wiley Online Library
Objective Antiphospholipid antibodies (aPL), especially those targeting β2‐glycoprotein I
(β2GPI), are well known to activate endothelial cells, monocytes, and platelets, with …

Diagnosing antiphospholipid syndrome:'extra-criteria'manifestations and technical advances

S Sciascia, MC Amigo, D Roccatello… - Nature Reviews …, 2017 - nature.com
First described in the early 1980s, antiphospholipid syndrome (APS) is a unique form of
acquired autoimmune thrombophilia in which patients present with clinical features of …

In vivo role of neutrophil extracellular traps in antiphospholipid antibody–mediated venous thrombosis

H Meng, S Yalavarthi, Y Kanthi, LF Mazza… - Arthritis & …, 2017 - Wiley Online Library
Objective Antiphospholipid syndrome (APS) is a leading acquired cause of thrombotic
events. Although antiphospholipid antibodies have been shown to promote thrombosis in …

Development of a new international antiphospholipid syndrome classification criteria phase I/II report: generation and reduction of candidate criteria

M Barbhaiya, S Zuily, Y Ahmadzadeh… - Arthritis care & …, 2021 - Wiley Online Library
Objective An international multidisciplinary initiative, jointly supported by the American
College of Rheumatology and European Alliance of Associations for Rheumatology, is …

The relevance of “non-criteria” clinical manifestations of antiphospholipid syndrome: 14th international congress on antiphospholipid antibodies technical task force …

MM Abreu, A Danowski, DG Wahl, MC Amigo… - Autoimmunity …, 2015 - Elsevier
The purpose of this task force was to critically analyze nine non-criteria manifestations of
APS to support their inclusion as APS classification criteria. The Task Force Members …

[HTML][HTML] The role of beta-2-glycoprotein I in health and disease associating structure with function: More than just APS

T McDonnell, C Wincup, I Buchholz, C Pericleous… - Blood reviews, 2020 - Elsevier
Abstract Beta-2-Glycoprotein I (β2GPI) plays a number of essential roles throughout the
body. β2GPI, C-reactive protein and thrombomodulin are the only three proteins that …

[HTML][HTML] Moonlighting chromatin: when DNA escapes nuclear control

J Singh, M Boettcher, M Dölling, A Heuer… - Cell Death & …, 2023 - nature.com
Extracellular chromatin, for example in the form of neutrophil extracellular traps (NETs), is an
important element that propels the pathological progression of a plethora of diseases. DNA …

[PDF][PDF] Coagulopathy of COVID-19 and antiphospholipid antibodies

NT Connell, EM Battinelli, JM Connors - J Thromb Haemost, 2020 - sah.org.ar
Recently in the Journal of Thrombosis and Haemostasis, Harzallah and colleagues report
the results of antiphospholipid antibody testing in a series of 56 patients with confirmed or …