Although the first chiral organosulfur compounds were obtained at the beginning of this
century, they have received more attention since the early 1960s. Initially, chiral sulfur …

With modern methods for asymmetric catalysis breaking ground, the use of chiral auxiliaries
seems to be old-fashioned and rather inefficient. However, for many transformations, chiral …

Aliphatic amines strongly coordinate, and therefore easily inhibit, the activity of transition-
metal catalysts, posing a marked challenge to nitrogen-hydrogen (N–H) insertion reactions …

The first catalytic asymmetric cross-coupling of α-halo carbonyl compounds with aryl metal
reagents has been developed, thereby generating synthetically useful α-aryl carboxylic acid …

Cyclopropanes provide important design elements in medicinal chemistry and are widely
present in drug compounds. Here we describe a strategy and extensive synthetic studies for …

A new flavin catalyst 2 immobilized in an ionic liquid ([BMIm] PF6) was used for the highly
selective oxidation of sulfides to sulfoxides by hydrogen peroxide. The sulfoxides were …

Sulfonimidamides lead efficiently to nitrenes and have been converted to sulfimides,
sulfoximines, and aziridines in good yields, through a copper-mediated multicomponent …

A general and efficient method for the synthesis of cyclic sulfinates and sulfinamides based
on intramolecular homolytic substitution (SHi) at the sulfur atom by aryl or alkyl radicals is …

With a consecutive" asymmetric allylic alkylation (AAA)/cross-metathesis (CM)/conjugate
addition (CA)" protocol it is possible to synthesize either stereoisomer of compounds …

Cyclooxygenase-2 (COX-2) oxygenates arachidonic acid and the endocannabinoids 2-
arachidonoylglycerol (2-AG) and arachidonoylethanolamide (AEA). We recently reported …