This article presents the revised consensus criteria for the diagnosis of frontotemporal
dysfunction in amyotrophic lateral sclerosis (ALS) based on an international research …

Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease that results in
progressive loss of bulbar and limb function. Patients typically die from respiratory failure …

This study presents the Edinburgh Cognitive and Behavioural ALS Screen (ECAS),
developed for ALS patients with physical disability for use by health care professionals. The …

Objective To elucidate the relationship between disease stage in amyotrophic lateral
sclerosis (ALS), as measured with the King's Clinical Staging System, and cognitive and …

Increased awareness of cognitive and behavioural change in amyotrophic lateral sclerosis
has been driven by various clinic-based and population-based studies. A frontotemporal …

Apathy is both a symptom and syndrome prevalent in neurodegenerative disease, including
motor system disorders, that affects motivation to display goal directed functions. Levy and …

This study presents the Italian validation of the recently developed Edinburgh Cognitive and
Behavioural ALS Screen (ECAS), a short screen for cognitive/behavioural alterations in …

It is now well recognized that, in addition to motor impairment, amyotrophic lateral sclerosis
(ALS) may cause extra-motor clinical signs and symptoms. These can include the alteration …

There is increasing evidence that amyotrophic lateral sclerosis (ALS) and frontotemporal
dementia (FTD) lie on a clinical, pathological and genetic continuum with patients of one …

Aim Apathy is a prominent symptom of amyotrophic lateral sclerosis (ALS), but measurement
is confounded by physical disability. Furthermore, it has been traditionally measured as a …