A systematic analysis of all naturally-occurring glycosylated bacterial secondary metabolites
reported in the scientific literature up through early 2013 is presented. This comprehensive …

Type II polyketide synthases: gaining a deeper insight into enzymatic teamwork Page 1
REVIEW www.rsc.org/npr | Natural Product Reports Type II polyketide synthases: gaining a …

Covering: 1997 to 2010 The angucycline group is the largest group of type II PKS-
engineered natural products, rich in biological activities and chemical scaffolds. This …

Plants, marine organisms, and microorganisms have evolved complex chemical defense
and signaling systems that are designed to protect them from predators and provide other …

Polyketide (PK) and nonribosomal peptides (NRP), constructed on multimodular enzymatic
assembly lines, often attain the conformations that establish biological activity by cyclization …

Covering: 2004. Previous review: Nat. Prod. Rep., 2005, 22, 15This review covers the
literature published in 2004 for marine natural products, with 693 citations (491 for the …

Many biologically active small‐molecule natural products produced by microorganisms
derive their activities from sugar substituents. Changing the structures of these sugars can …

Covering: the literature up to April 2005The focus of this review is to highlight the structure,
bioactivity and biosynthesis of naturally occurring aryl-C-glycosides. General synthetic …

Covering: 1985–2002. This review covers the highlights of combinatorial biosynthesis
applied on post-polyketide synthase modifying enzymes, such as oxygenases …

Natural products with antibiotic activity have been central agents in human therapeutics over
the past fifty years. They are likely to remain crucial in the decades to come. These …