Tens of millions of contrast-enhanced magnetic resonance imaging (MRI) exams are
performed annually around the world. The contrast agents, which improve diagnostic …

Acidic extracellular pH is a major feature of tumor tissue, extracellular acidification being
primarily considered to be due to lactate secretion from anaerobic glycolysis …

Zeta potential is a scientific term for electrokinetic potential in colloidal systems which has a
major effect on the various properties of nano-drug delivery systems. Presently, colloidal …

Nanoparticle-based diagnosis–therapy integrative systems represent an emerging
approach to cancer treatment. However, the diagnostic sensitivity, treatment efficacy, and …

Our desire to understand how the individual molecules that make up cells organize, interact,
and communicate to form living systems has led to the burgeoning field of chemical biology …

Tumor DNA mismatch repair (MMR) deficiency testing is important to the identification of
Lynch syndrome and decision making regarding adjuvant chemotherapy in stage II …

Challenges for Molecular Magnetic Resonance Imaging | Chemical Reviews ACS ACS
Publications C&EN CAS Find my institution Log In Chemical Reviews ACS Publications. Most …

Studies over the last few decades have demonstrated that the intracellular pH of solid
tumors is maintained within a range of 7.0–7.2, whereas the extracellular pH is acidic. A low …

A comprehensive classification of contrast agents currently used or under development for
magnetic resonance imaging (MRI) is presented. Agents based on small chelates …

In this review we examine the mechanisms (causes) underlying the increased glucose
consumption observed in tumors within a teleological context (consequences). In other …