Host and viral determinants of influenza A virus species specificity
Influenza A viruses cause pandemics when they cross between species and an
antigenically novel virus acquires the ability to infect and transmit between these new hosts …
antigenically novel virus acquires the ability to infect and transmit between these new hosts …
The evolution and future of influenza pandemic preparedness
WN Harrington, CM Kackos, RJ Webby - Experimental & molecular …, 2021 - nature.com
The influenza virus is a global threat to human health causing unpredictable yet recurring
pandemics, the last four emerging over the course of a hundred years. As our knowledge of …
pandemics, the last four emerging over the course of a hundred years. As our knowledge of …
GISAID: Global initiative on sharing all influenza data–from vision to reality
Y Shu, J McCauley - Eurosurveillance, 2017 - eurosurveillance.org
Ten years ago, a correspondence [1, 2], signed by more than 70 championed 'A global
initiative on sharing avian flu data'(GISAID)[3], leading to the GISAID Initiative in 2008. What …
initiative on sharing avian flu data'(GISAID)[3], leading to the GISAID Initiative in 2008. What …
Host and viral traits predict zoonotic spillover from mammals
The majority of human emerging infectious diseases are zoonotic, with viruses that originate
in wild mammals of particular concern (for example, HIV, Ebola and SARS),,. Understanding …
in wild mammals of particular concern (for example, HIV, Ebola and SARS),,. Understanding …
Pathways to zoonotic spillover
Zoonotic spillover, which is the transmission of a pathogen from a vertebrate animal to a
human, presents a global public health burden but is a poorly understood phenomenon …
human, presents a global public health burden but is a poorly understood phenomenon …
The future of zoonotic risk prediction
CJ Carlson, MJ Farrell, Z Grange… - … of the Royal …, 2021 - royalsocietypublishing.org
In the light of the urgency raised by the COVID-19 pandemic, global investment in wildlife
virology is likely to increase, and new surveillance programmes will identify hundreds of …
virology is likely to increase, and new surveillance programmes will identify hundreds of …
The phylogenomics of evolving virus virulence
JL Geoghegan, EC Holmes - Nature Reviews Genetics, 2018 - nature.com
How virulence evolves after a virus jumps to a new host species is central to disease
emergence. Our current understanding of virulence evolution is based on insights drawn …
emergence. Our current understanding of virulence evolution is based on insights drawn …
Host traits shape virome composition and virus transmission in wild small mammals
YM Chen, SJ Hu, XD Lin, JH Tian, JX Lv, MR Wang… - Cell, 2023 - cell.com
Bats, rodents, and shrews are the most important animal sources of human infectious
diseases. However, the evolution and transmission of viruses among them remain largely …
diseases. However, the evolution and transmission of viruses among them remain largely …
MERS-CoV spillover at the camel-human interface
Middle East respiratory syndrome coronavirus (MERS-CoV) is a zoonotic virus from camels
causing significant mortality and morbidity in humans in the Arabian Peninsula. The …
causing significant mortality and morbidity in humans in the Arabian Peninsula. The …
Predicting virus emergence amid evolutionary noise
JL Geoghegan, EC Holmes - Open biology, 2017 - royalsocietypublishing.org
The study of virus disease emergence, whether it can be predicted and how it might be
prevented, has become a major research topic in biomedicine. Here we show that efforts to …
prevented, has become a major research topic in biomedicine. Here we show that efforts to …