Host and viral determinants of influenza A virus species specificity

JS Long, B Mistry, SM Haslam… - Nature Reviews …, 2019 - nature.com
Influenza A viruses cause pandemics when they cross between species and an
antigenically novel virus acquires the ability to infect and transmit between these new hosts …

The evolution and future of influenza pandemic preparedness

WN Harrington, CM Kackos, RJ Webby - Experimental & molecular …, 2021 - nature.com
The influenza virus is a global threat to human health causing unpredictable yet recurring
pandemics, the last four emerging over the course of a hundred years. As our knowledge of …

GISAID: Global initiative on sharing all influenza data–from vision to reality

Y Shu, J McCauley - Eurosurveillance, 2017 - eurosurveillance.org
Ten years ago, a correspondence [1, 2], signed by more than 70 championed 'A global
initiative on sharing avian flu data'(GISAID)[3], leading to the GISAID Initiative in 2008. What …

Host and viral traits predict zoonotic spillover from mammals

KJ Olival, PR Hosseini, C Zambrana-Torrelio, N Ross… - Nature, 2017 - nature.com
The majority of human emerging infectious diseases are zoonotic, with viruses that originate
in wild mammals of particular concern (for example, HIV, Ebola and SARS),,. Understanding …

Pathways to zoonotic spillover

RK Plowright, CR Parrish, H McCallum… - Nature Reviews …, 2017 - nature.com
Zoonotic spillover, which is the transmission of a pathogen from a vertebrate animal to a
human, presents a global public health burden but is a poorly understood phenomenon …

The future of zoonotic risk prediction

CJ Carlson, MJ Farrell, Z Grange… - … of the Royal …, 2021 - royalsocietypublishing.org
In the light of the urgency raised by the COVID-19 pandemic, global investment in wildlife
virology is likely to increase, and new surveillance programmes will identify hundreds of …

The phylogenomics of evolving virus virulence

JL Geoghegan, EC Holmes - Nature Reviews Genetics, 2018 - nature.com
How virulence evolves after a virus jumps to a new host species is central to disease
emergence. Our current understanding of virulence evolution is based on insights drawn …

Host traits shape virome composition and virus transmission in wild small mammals

YM Chen, SJ Hu, XD Lin, JH Tian, JX Lv, MR Wang… - Cell, 2023 - cell.com
Bats, rodents, and shrews are the most important animal sources of human infectious
diseases. However, the evolution and transmission of viruses among them remain largely …

MERS-CoV spillover at the camel-human interface

G Dudas, LM Carvalho, A Rambaut, T Bedford - elife, 2018 - elifesciences.org
Middle East respiratory syndrome coronavirus (MERS-CoV) is a zoonotic virus from camels
causing significant mortality and morbidity in humans in the Arabian Peninsula. The …

Predicting virus emergence amid evolutionary noise

JL Geoghegan, EC Holmes - Open biology, 2017 - royalsocietypublishing.org
The study of virus disease emergence, whether it can be predicted and how it might be
prevented, has become a major research topic in biomedicine. Here we show that efforts to …