Background The function of major histocompatibility complex (MHC) molecules is to bind
peptide fragments derived from genomic mutations or pathogens and display them on the …

As a non-classic major histocompatibility complex (MHC) class I molecule, human leukocyte
antigen G (HLA-G) is expressed in fetal-maternal interface and immunoprivileged site only in …

Human leukocyte antigen (HLA) molecules are essential for anti-tumor immunity, as they
display tumor-derived peptides to drive tumor eradication by cytotoxic T lymphocytes. HLA …

The non-classical human leukocyte antigen (HLA)-G exerts immune-suppressive properties
modulating both NK and T cell responses. While it is physiologically expressed at the …

As BRAF, TERT, HLA-G, and microRNAs have been individually associated with papillary
thyroid carcinoma (PTC), we aimed to evaluate the individual and collaborative role of these …

Purpose Papillary thyroid carcinoma (PTC) is the most frequent subtype of thyroid cancer;
Hashimoto's thyroiditis (HT), autoimmune disease, commonly affects the thyroid gland; there …

Background Interleukin (IL)-17A has a dual role in tumor immunity, promotes anti-tumor
responses and facilitates angiogenesis by interacting with IL-17 receptor A (IL-17RA) …

Objectives The incidence of papillary thyroid carcinoma (PTC) has increased more rapidly
than that of any other cancer type in China. Early indicators with high sensitivity and …

Natural killer (NK) cells, key antitumor effectors of the innate immune system, are endowed
with the unique ability to spontaneously eliminate cells undergoing a neoplastic …

Purpose An in-depth understanding of the mechanism of thyroid cancer progression will
help identify patients with thyroid cancer with a high risk of recurrence and metastasis …