Guts and gall: bile acids in regulation of intestinal epithelial function in health and disease
Epithelial cells line the entire surface of the gastrointestinal tract and its accessory organs
where they primarily function in transporting digestive enzymes, nutrients, electrolytes, and …
where they primarily function in transporting digestive enzymes, nutrients, electrolytes, and …
Tauroursodeoxycholate—bile acid with chaperoning activity: molecular and cellular effects and therapeutic perspectives
M Kusaczuk - Cells, 2019 - mdpi.com
Tauroursodeoxycholic acid (TUDCA) is a naturally occurring hydrophilic bile acid that has
been used for centuries in Chinese medicine. Chemically, TUDCA is a taurine conjugate of …
been used for centuries in Chinese medicine. Chemically, TUDCA is a taurine conjugate of …
Ursodeoxycholic acid and lithocholic acid exert anti-inflammatory actions in the colon
JBJ Ward, NK Lajczak, OB Kelly… - American Journal …, 2017 - journals.physiology.org
Inflammatory bowel diseases (IBD) comprise a group of common and debilitating chronic
intestinal disorders for which currently available therapies are often unsatisfactory. The …
intestinal disorders for which currently available therapies are often unsatisfactory. The …
From dried bear bile to molecular investigation: a systematic review of the effect of bile acids on cell apoptosis, oxidative stress and inflammation in the brain, across …
F Huang, CM Pariante, A Borsini - Brain, behavior, and immunity, 2022 - Elsevier
Bile acids, mainly ursodeoxycholic acid (UDCA) and its conjugated species
glycoursodeoxycholic acid (GUDCA) and tauroursodeoxycholic acid (TUDCA) have long …
glycoursodeoxycholic acid (GUDCA) and tauroursodeoxycholic acid (TUDCA) have long …
[HTML][HTML] Recent advances on FXR-targeting therapeutics
K Panzitt, G Zollner, HU Marschall, M Wagner - Molecular and cellular …, 2022 - Elsevier
The bile acid receptor FXR has emerged as a bona fide drug target for chronic cholestatic
and metabolic liver diseases, ahead of all non-alcoholic fatty liver disease (NAFLD). FXR is …
and metabolic liver diseases, ahead of all non-alcoholic fatty liver disease (NAFLD). FXR is …
Deep sequencing of plant and animal DNA contained within traditional Chinese medicines reveals legality issues and health safety concerns
ML Coghlan, J Haile, J Houston, DC Murray… - PLoS …, 2012 - journals.plos.org
Traditional Chinese medicine (TCM) has been practiced for thousands of years, but only
within the last few decades has its use become more widespread outside of Asia. Concerns …
within the last few decades has its use become more widespread outside of Asia. Concerns …
Ursodeoxycholic acid and cancer: From chemoprevention to chemotherapy
JF Goossens, C Bailly - Pharmacology & therapeutics, 2019 - Elsevier
Ursodeoxycholic acid (UDCA) is a secondary bile acid issued from the transformation of
(cheno) deoxycholic acid by intestinal bacteria, acting as a key regulator of the intestinal …
(cheno) deoxycholic acid by intestinal bacteria, acting as a key regulator of the intestinal …
Human-wildlife conflicts influence attitudes but not necessarily behaviors: Factors driving the poaching of bears in China
Human-wildlife conflicts often spur retaliatory killing, which may be a major threat to some
wildlife species. Asiatic black bears depredate crops and livestock and also attack humans …
wildlife species. Asiatic black bears depredate crops and livestock and also attack humans …
Taking a more nuanced look at behavior change for demand reduction in the illegal wildlife trade
L Thomas‐Walters, D Veríssimo… - … Science and Practice, 2020 - Wiley Online Library
The illegal wildlife trade threatens the future of many species, and undermines economies
and livelihoods. Conservationists have largely responded with supply‐side interventions …
and livelihoods. Conservationists have largely responded with supply‐side interventions …
[HTML][HTML] Latest development in the synthesis of ursodeoxycholic acid (UDCA): a critical review
F Tonin, IWCE Arends - Beilstein journal of organic chemistry, 2018 - beilstein-journals.org
Ursodeoxycholic acid (UDCA) is a pharmaceutical ingredient widely used in clinics. As bile
acid it solubilizes cholesterol gallstones and improves the liver function in case of cholestatic …
acid it solubilizes cholesterol gallstones and improves the liver function in case of cholestatic …