Practical considerations in medical cannabis administration and dosing

CA MacCallum, EB Russo - European journal of internal medicine, 2018 - Elsevier
Cannabis has been employed medicinally throughout history, but its recent legal prohibition,
biochemical complexity and variability, quality control issues, previous dearth of …

New approaches and challenges to targeting the endocannabinoid system

V Di Marzo - Nature Reviews Drug Discovery, 2018 - nature.com
The endocannabinoid signalling system was discovered because receptors in this system
are the targets of compounds present in psychotropic preparations of Cannabis sativa. The …

Minor cannabinoids: biosynthesis, molecular pharmacology and potential therapeutic uses

KB Walsh, AE McKinney, AE Holmes - Frontiers in Pharmacology, 2021 - frontiersin.org
The medicinal use of Cannabis sativa L. can be traced back thousands of years to ancient
China and Egypt. While marijuana has recently shown promise in managing chronic pain …

Hempseed in food industry: Nutritional value, health benefits, and industrial applications

W Leonard, P Zhang, D Ying… - Comprehensive reviews in …, 2020 - Wiley Online Library
Hemp (Cannabis sativa L.) seeds have been consumed in Asian communities since
prehistoric times. Recently, Australia, Canada, and the United States have legalized the …

Cannabis pharmacology: the usual suspects and a few promising leads

EB Russo, J Marcu - Advances in pharmacology, 2017 - Elsevier
The golden age of cannabis pharmacology began in the 1960s as Raphael Mechoulam and
his colleagues in Israel isolated and synthesized cannabidiol, tetrahydrocannabinol, and …

Medicinal properties of cannabinoids, terpenes, and flavonoids in cannabis, and benefits in migraine, headache, and pain: an update on current evidence and …

EP Baron - Headache: The Journal of Head and Face Pain, 2018 - Wiley Online Library
Background Comprehensive literature reviews of historical perspectives and evidence
supporting cannabis/cannabinoids in the treatment of pain, including migraine and …

In vitro and in vivo pharmacological activity of minor cannabinoids isolated from Cannabis sativa

A Zagzoog, KA Mohamed, HJJ Kim, ED Kim… - Scientific Reports, 2020 - nature.com
The Cannabis sativa plant contains more than 120 cannabinoids. With the exceptions of∆ 9-
tetrahydrocannabinol (∆ 9-THC) and cannabidiol (CBD), comparatively little is known about …

Cannabis: Chemistry, extraction and therapeutic applications

F Pattnaik, S Nanda, S Mohanty, AK Dalai, V Kumar… - Chemosphere, 2022 - Elsevier
Cannabis, a genus of perennial indigenous plants is well known for its recreational and
medicinal activities. Cannabis and its derivatives have potential therapeutic activities to treat …

Cannabidiol and other non-psychoactive cannabinoids for prevention and treatment of gastrointestinal disorders: useful nutraceuticals?

V Martínez, A Iriondo De-Hond, F Borrelli… - International Journal of …, 2020 - mdpi.com
Cannabis sativa is an aromatic annual flowering plant with several botanical varieties, used
for different purposes, like the production of fibers, the production of oil from the seeds, and …

Patterns of medicinal cannabis use, strain analysis, and substitution effect among patients with migraine, headache, arthritis, and chronic pain in a medicinal cannabis …

EP Baron, P Lucas, J Eades, O Hogue - The journal of headache and pain, 2018 - Springer
Background Medicinal cannabis registries typically report pain as the most common reason
for use. It would be clinically useful to identify patterns of cannabis treatment in migraine and …