Candida sp. Infections in Patients with Diabetes Mellitus

CF Rodrigues, ME Rodrigues, M Henriques - Journal of clinical medicine, 2019 - mdpi.com
Candidiasis has increased substantially worldwide over recent decades and is a significant
cause of morbidity and mortality, especially among critically ill patients. Diabetes mellitus …

An Update on Candida tropicalis Based on Basic and Clinical Approaches

DL Zuza-Alves, WP Silva-Rocha… - Frontiers in …, 2017 - frontiersin.org
Candida tropicalis has emerged as one of the most important Candida species. It has been
widely considered the second most virulent Candida species, only preceded by C. albicans …

Components of the calcium-calcineurin signaling pathway in fungal cells and their potential as antifungal targets

S Liu, Y Hou, W Liu, C Lu, W Wang, S Sun - Eukaryotic cell, 2015 - Am Soc Microbiol
In recent years, the emergence of fungal resistance has become frequent, partly due to the
widespread clinical use of fluconazole, which is minimally toxic and effective in the …

Gentian violet: a 19th century drug re‐emerges in the 21st century

AM Maley, JL Arbiser - Experimental dermatology, 2013 - Wiley Online Library
Gentian violet (GV) has a long and varied history as a medicinal agent. Historically used as
an antibacterial and antifungal, recent reports have shown its utility as an antitypranosomal …

Distribution of Candida albicans and non-albicans Candida species isolated in different clinical samples and their in vitro antifungal suscetibity profile in Ethiopia

E Seyoum, A Bitew, A Mihret - BMC infectious diseases, 2020 - Springer
Background The spectrum of yeasts and their antifungal susceptibility profile are poorly
known and treatment of fungal disease has remained empirical. The aim of this study is to …

Combination of fluconazole with non-antifungal agents: a promising approach to cope with resistant Candida albicans infections and insight into new antifungal agent …

S Liu, Y Hou, X Chen, Y Gao, H Li, S Sun - International journal of …, 2014 - Elsevier
The past decades have witnessed a dramatic increase in invasive fungal infections,
especially candidiasis. Despite the development of more effective new antifungal agents …

State of evidence on oral health problems in diabetic patients: a critical review of the literature

MÁ González-Moles, P Ramos-García - Journal of Clinical Medicine, 2021 - mdpi.com
Diabetes mellitus (DM) is a global health problem, having recognized that in the next 20
years the number of diabetic patients in the world will increase to 642 million. DM exerts …

Discovery of BRD4–HDAC Dual Inhibitors with Improved Fungal Selectivity and Potent Synergistic Antifungal Activity against Fluconazole-Resistant Candida albicans

Z Li, Y Huang, J Tu, W Yang, N Liu… - Journal of Medicinal …, 2023 - ACS Publications
Over the past several decades, invasive fungal infections, especially candidiasis, have
caused dramatic morbidity and mortality due to ineffective antifungal drugs and severe drug …

Azole resistance in dermatophytes: prevalence and mechanism of action

M Ghannoum - Journal of the American Podiatric Medical …, 2016 - Am Podiatric Med Assoc
Azole antifungal agents (eg, fluconazole and itraconazole) have been widely used to treat
superficial fungal infections caused by dermatophytes and, unlike the allylamines (such as …

Oropharyngeal candidosis in HIV-infected patients—an update

S Patil, B Majumdar, SC Sarode, GS Sarode… - Frontiers in …, 2018 - frontiersin.org
Oropharyngeal candidosis (OPC) is an opportunistic fungal infection that is commonly found
in HIV-infected patients, even in the twenty-first century. Candida albicans is the main …