Physical stimuli are essential for the function of eukaryotic cells, and changes in physical
signals are important elements in normal tissue development as well as in disease initiation …

Integrin adhesion complexes (IACs) have evolved over millions of years to integrate
metazoan cells physically with their microenvironment. It is presumed that the simultaneous …

Cells and organelles are delimited by lipid bilayers in which high deformability is essential to
many cell processes, including motility, endocytosis and cell division. Membrane tension is …

The linkage of cells to their microenvironment is mediated by a series of bonds that
dynamically engage and disengage, in what has been conceptualized as the molecular …

Cell fate transitions are frequently accompanied by changes in cell shape and mechanics.
However, how cellular mechanics affects the instructive signaling pathways controlling cell …

Membrane tension is thought to be a long-range integrator of cell physiology. Membrane
tension has been proposed to enable cell polarity during migration through front-back …

Cells are constantly submitted to external mechanical stresses, which they must withstand
and respond to. By forming a physical boundary between cells and their environment that is …

The cell surface is a mechanobiological unit that encompasses the plasma membrane, its
interacting proteins, and the complex underlying cytoskeleton. Recently, attention has been …

It is increasingly clear that mechanotransduction pathways play important roles in regulating
fundamental cellular functions. Of the basic mechanical functions, the determination of …

Abstract The identification of Tunneling Nanotubes (TNTs) and TNT‐like structures signified
a critical turning point in the field of cell‐cell communication. With hypothesized roles in …