Traumatic spinal cord injury (SCI) is a life changing neurological condition with substantial
socioeconomic implications for patients and their care-givers. Recent advances in medical …

Body-weight supported locomotor training (BWST) promotes recovery of load-bearing
stepping in lower mammals, but its efficacy in individuals with a spinal cord injury (SCI) is …

Neuroprotection refers to the attenuation of pathophysiological processes triggered by acute
injury to minimize secondary damage. The development of neuroprotective treatments …

Large animal and primate models of spinal cord injury (SCI) are being increasingly utilized
for the testing of novel therapies. While these represent intermediary animal species …

Because there is no curative treatment for spinal cord injury, establishing an ideal animal
model is important to identify injury mechanisms and develop therapies for individuals …

In this narrative review we aimed to assess the usefulness of the different animal models in
identifying injury mechanisms and developing therapies for humans suffering from spinal …

Spinal cord injury (SCI) is a devastating condition that affects approximately 294,000 people
in the USA and several millions worldwide. The corticospinal motor circuitry plays a major …

Animal models are necessary to identify pathological changes and help assess therapeutic
outcomes following spinal cord injury (SCI). Small animal models offer value in research in …

Animal models are used to examine the results of experimental spinal cord injury.
Alterations in spinal cord blood supply caused by complex spinal cord injuries contribute …

Biomaterials may enhance neural repair after spinal cord injury (SCI) and testing their
functionality in large animals is essential to achieve successful clinical translation. This work …