Unraveling plant natural chemical diversity for drug discovery purposes

E Lautié, O Russo, P Ducrot, JA Boutin - Frontiers in pharmacology, 2020 - frontiersin.org
The screening and testing of extracts against a variety of pharmacological targets in order to
benefit from the immense natural chemical diversity is a concern in many laboratories …

Naturally occurring acetylcholinesterase inhibitors and their potential use for Alzheimer's disease therapy

TC Santos, TM Gomes, BAS Pinto… - Frontiers in …, 2018 - frontiersin.org
Alzheimer's disease (AD) is a main cause of dementia, accounting for up to 75% of all
dementia cases. Pathophysiological processes described for AD progression involve …

[HTML][HTML] Potential therapeutic natural products against Alzheimer's disease with Reference of Acetylcholinesterase

S Ahmed, ST Khan, MK Zargaham, AU Khan… - Biomedicine & …, 2021 - Elsevier
Abstract Alzheimer's disease (AD), is the most common type of dementia primarily affecting
the later years of life. Its prevalence is likely to increase in any aging population and will be a …

Inhibitory Effects of Raw-Extract Centella asiatica (RECA) on Acetylcholinesterase, Inflammations, and Oxidative Stress Activities via In Vitro and In Vivo

ZZ Hafiz, MAM Amin, RM Johari James, LK Teh… - Molecules, 2020 - mdpi.com
Centella asiatica (C. asiatica) is one of the medicinal plants that has been reported to exert
comprehensive neuroprotection in vitro and in vivo. In view of this, the present study was …

Chemical Composition and Biological Properties of Two Jatropha Species: Different Parts and Different Extraction Methods

G Zengin, MF Mahomoodally, KI Sinan, G Ak… - Antioxidants, 2021 - mdpi.com
Jatropha L. species, in particular, J. curcas and J. gossypiifolia, are well known medicinal
plants used for treating various diseases. In the present study, leaf and stem bark extracts of …

Bougainvillea glabra (choisy): A comprehensive review on botany, traditional uses, phytochemistry, pharmacology and toxicity

H Saleem, A Usman, MF Mahomoodally… - Journal of …, 2021 - Elsevier
Abstract Ethnopharmacological relevance Bougainvillea glabra (Choisy).(Family:
Nyctinaginacea) is a valuable ornamental plant with culinary uses and also utilized in …

Jatropha gossypiifolia L. and its biologically active metabolites: A mini review

Q Wu, J Patocka, E Nepovimova, K Kuca - Journal of ethnopharmacology, 2019 - Elsevier
Ethnopharmacological relevance Jatropha gossypiifolia L.(Euphorbiaceae) is popularly
known as bellyache bush or black physic nut and is widely used in local/traditional medicine …

[HTML][HTML] Chemical constituents and biological activities of African medicinal tree Sterculia setigera Delile stem bark

K Alshambaty, S Yagi, AA Elbashir, H Schohn… - South African Journal of …, 2021 - Elsevier
Stem bark of Sterculia setigera Delile, family Sterculiaceae, is used in traditional medicine in
Sudan and other African countries to treat various diseases. This study aimed to investigate …

In Vitro Anti‐AChE, Anti‐BuChE, and Antioxidant Activity of 12 Extracts of Eleutherococcus Species

D Załuski, R Kuźniewski - Oxidative Medicine and Cellular …, 2016 - Wiley Online Library
Neurodegenerative diseases are one of the most occurring diseases in developed and
developing countries. The aim of this work focused on the screening of the natural inhibitors …

[HTML][HTML] Chemical Profiling, in-vitro biological evaluation and molecular docking studies of Ruellia tweediana: An unexplored plant

S Kanwal, S Ahmad, MY Begum, A Siddiqua… - Saudi Pharmaceutical …, 2024 - Elsevier
Many Ruellia species have been utilized in traditional medicine and despite the prevalent
use of Ruellia tweediana in folk medicine, its antioxidant potential and polyphenol content …