Apicomplexan parasites are a group of eukaryotic protozoans with diverse biology that have
affected human health like no other group of parasites. These obligate intracellular parasites …

Apicomplexan parasites exhibit tremendous diversity in much of their fundamental cell
biology, but study of these organisms using light microscopy is often hindered by their small …

Microtubules are a ubiquitous eukaryotic cytoskeletal element typically consisting of 13
protofilaments arranged in a hollow cylinder. This arrangement is considered the canonical …

During its asexual blood stage, P. falciparum replicates via schizogony, wherein dozens of
daughter cells are formed within a single parent. The basal complex, a contractile ring that …

Malaria remains a leading cause of death and disease in many tropical and subtropical
regions of the world. Due to the alarming spread of resistance to almost all available …

Plasmodium falciparum encounters significant population bottlenecks when being
transmitted between humans and mosquitoes. To overcome those, it undergoes several …

For its replication within red blood cells, the malaria parasite depends on a highly active and
regulated lipid metabolism. Enzymes involved in lipid metabolic processes such as …

Apicomplexan parasites have immense impacts on humanity, but their basic cellular
processes are often poorly understood. Where endocytosis occurs in these cells, how …

The malaria-causing parasite, Plasmodium falciparum completely remodels its host red
blood cell (RBC) through the export of several hundred parasite proteins, including …

Faithful chromosome segregation of 8 duplicated haploid genomes into 8 daughter gametes
is essential for male gametogenesis and mosquito transmission of Plasmodium …