Nanozymes-recent development and biomedical applications

X Ren, D Chen, Y Wang, H Li, Y Zhang, H Chen… - Journal of …, 2022 - Springer
Nanozyme is a series of nanomaterials with enzyme-mimetic activities that can proceed with
the catalytic reactions of natural enzymes. In the field of biomedicine, nanozymes are …

The uptake of metal–organic frameworks: A journey into the cell

E Linnane, S Haddad, F Melle, Z Mei… - Chemical Society …, 2022 - pubs.rsc.org
The application of metal–organic frameworks (MOFs) in drug delivery has advanced rapidly
over the past decade, showing huge progress in the development of novel systems …

Ceria‐based therapeutic antioxidants for biomedical applications

YG Kim, Y Lee, N Lee, M Soh, D Kim… - Advanced …, 2024 - Wiley Online Library
The growing interest in nanomedicine over the last 20 years has carved out a research field
called “nanocatalytic therapy,” where catalytic reactions mediated by nanomaterials are …

A thrombin‐activated peptide‐templated nanozyme for remedying ischemic stroke via thrombolytic and neuroprotective actions

Z Wang, Y Zhao, Y Hou, G Tang, R Zhang… - Advanced …, 2024 - Wiley Online Library
Ischemic stroke (IS) is one of the most common causes of disability and death. Thrombolysis
and neuroprotection are two current major therapeutic strategies to overcome ischemic and …

A nonferrous ferroptosis-like strategy for antioxidant inhibition–synergized nanocatalytic tumor therapeutics

C Wu, Z Liu, Z Chen, D Xu, L Chen, H Lin, J Shi - Science advances, 2021 - science.org
Ferroptosis, an emerging type of cell death found in the past decades, features specifically
lipid peroxidation during the cell death process commonly by iron accumulation …

Chiral metal-organic frameworks incorporating nanozymes as neuroinflammation inhibitors for managing Parkinson's disease

W Jiang, Q Li, R Zhang, J Li, Q Lin, J Li, X Zhou… - Nature …, 2023 - nature.com
Nanomedicine-based anti-neuroinflammation strategy has become a promising dawn of
Parkinson's disease (PD) treatment. However, there are significant gaps in our …

Capsulation of AuNCs with AIE effect into metal–organic framework for the marriage of a fluorescence and colorimetric biosensor to detect organophosphorus …

Y Cai, H Zhu, W Zhou, Z Qiu, C Chen, A Qileng… - Analytical …, 2021 - ACS Publications
Organophosphorus pesticides (OPs) can inhibit the activity of acetylcholinesterase (AChE)
to induce neurological diseases. It is significant to exploit a rapid and sensitive strategy to …

Cerium oxide nanoparticles with antioxidative neurorestoration for ischemic stroke

X Li, Z Han, T Wang, C Ma, H Li, H Lei, Y Yang… - Biomaterials, 2022 - Elsevier
Oxidative stress and mitochondrial damage are the main mechanisms of ischemia-
reperfusion injury in ischemic stroke. Herein, cerium oxide nanoparticles with powerful free …

Defect engineering in nanozymes

Y Wu, W Xu, L Jiao, Y Tang, Y Chen, W Gu, C Zhu - Materials Today, 2022 - Elsevier
Due to the high stability, various synthesis strategies, low cost, and tunable performance,
nanozymes have gained much attention as the replacement of natural enzymes. To widen …

Nanozymes for regenerative medicine

X Mou, Q Wu, Z Zhang, Y Liu, J Zhang, C Zhang… - Small …, 2022 - Wiley Online Library
Nanozymes refer to nanomaterials that catalyze enzyme substrates into products under
relevant physiological conditions following enzyme kinetics. Compared to natural enzymes …