Role of serotonin in fish reproduction

P Prasad, S Ogawa, IS Parhar - Frontiers in neuroscience, 2015 - frontiersin.org
The neuroendocrine mechanism regulates reproduction through the hypothalamo-pituitary-
gonadal (HPG) axis which is evolutionarily conserved in vertebrates. The HPG axis is …

Origin and evolution of the neuroendocrine control of reproduction in vertebrates, with special focus on genome and gene duplications

S Dufour, B Quérat, H Tostivint… - Physiological …, 2020 - journals.physiology.org
In humans, as in the other mammals, the neuroendocrine control of reproduction is ensured
by the brain-pituitary gonadotropic axis. Multiple internal and environmental cues are …

GnRH dysregulation in polycystic ovarian syndrome (PCOS) is a manifestation of an altered neurotransmitter profile

N Chaudhari, M Dawalbhakta… - Reproductive Biology and …, 2018 - Springer
Background GnRH is the master molecule of reproduction that is influenced by several
intrinsic and extrinsic factors such as neurotransmitters and neuropeptides. Any alteration in …

Modulation of gonadotropin-releasing hormone neuron activity and secretion in mice by non-peptide neurotransmitters, gasotransmitters, and gliotransmitters

DJ Spergel - Frontiers in endocrinology, 2019 - frontiersin.org
Gonadotropin-releasing hormone (GnRH) neuron activity and GnRH secretion are essential
for fertility in mammals. Here, I review findings from mouse studies on the direct modulation …

The antidepressant fluoxetine (Prozac®) modulates estrogen signaling in the uterus and alters estrous cycles in mice

RR Domingues, MC Wiltbank, LL Hernandez - Molecular and cellular …, 2023 - Elsevier
Selective serotonin reuptake inhibitors (SSRI) are the most used antidepressants. However,
up to 80% of women taking SSRI suffer from sexual dysfunction. We investigated the effects …

The epigenetic role of HTR1A antagonist in facilitating GnRH expression for pubertal initiation control

S Zhou, Y Shen, S Zang, X Yin, P Li - Molecular Therapy-Nucleic Acids, 2021 - cell.com
Serotonin (5-hydroxytryptamine [5-HT]), a metabolite of tryptophan, acts on the components
of the hypothalamus-hypophysis-gonad axis and induces puberty delay in mammals via 5 …

Neurotransmitter, neuropeptide and gut peptide profile in PCOS-pathways contributing to the pathophysiology, food intake and psychiatric manifestations of PCOS

IR Ilie - Advances in Clinical Chemistry, 2020 - Elsevier
Polycystic ovary syndrome (PCOS) is a major health problem with a heterogeneous
hormone-imbalance and clinical presentation across the lifespan of women. Increased …

The role of neuropeptides and neurotransmitters on kisspeptin/kiss1r-signaling in female reproduction

S Saedi, A Khoradmehr, JSM Reza… - Journal of chemical …, 2018 - Elsevier
Reproductive function is regulated by the hypothalamic-pituitary-gonads (HPG) axis.
Hypothalamic neurons synthesizing kisspeptin play a fundamental role in the central …

Altered expression of genes encoding neurotransmitter receptors in GnRH neurons of proestrous mice

C Vastagh, A Rodolosse, N Solymosi… - Frontiers in cellular …, 2016 - frontiersin.org
Gonadotropin-releasing hormone (GnRH) neurons play a key role in the central regulation
of reproduction. In proestrous female mice, estradiol triggers the pre-ovulatory GnRH surge …

Social stress-induced serotonin dysfunction activates spexin in male Nile tilapia (Oreochromis Niloticus)

CH Lim, T Soga, IS Parhar - Proceedings of the National …, 2023 - National Acad Sciences
Social disturbance in interpersonal relationships is the primary source of stress in humans.
Spexin (SPX, SPX1a in cichlid), an evolutionarily conserved neuropeptide with diverse …