[HTML][HTML] Clinical development of BRAF plus MEK inhibitor combinations

V Subbiah, C Baik, JM Kirkwood - Trends in cancer, 2020 - cell.com
Genomic profiling shows that many solid tumors are characterized by specific driver
aberrations, and this has expanded the therapeutic options for many patients. The mitogen …

[HTML][HTML] Therapeutic advances in anaplastic thyroid cancer: a current perspective

S Saini, K Tulla, AV Maker, KD Burman, BS Prabhakar - Molecular cancer, 2018 - Springer
Thyroid cancer incidence is increasing at an alarming rate, almost tripling every decade. In
2017, it was the fifth most common cancer in women. Although the majority of thyroid tumors …

[HTML][HTML] KDM1A promotes thyroid cancer progression and maintains stemness through the Wnt/β-catenin signaling pathway

W Zhang, X Ruan, Y Li, J Zhi, L Hu, X Hou, X Shi… - Theranostics, 2022 - ncbi.nlm.nih.gov
Background: Cancer stem cells (CSCs) are highly tumorigenic, chemotherapy-resistant,
tumor growth-sustaining, and are implicated in tumor recurrence. Previous studies have …

[HTML][HTML] Long non-coding RNAs as the critical regulators of doxorubicin resistance in tumor cells

G Khalili-Tanha, M Moghbeli - Cellular & Molecular Biology Letters, 2021 - Springer
Resistance against conventional chemotherapeutic agents is one of the main reasons for
tumor relapse and poor clinical outcomes in cancer patients. Various mechanisms are …

[HTML][HTML] Recent advances in the management of anaplastic thyroid cancer

S De Leo, M Trevisan, L Fugazzola - Thyroid research, 2020 - Springer
Anaplastic thyroid cancer (ATC) is undoubtedly the thyroid cancer histotype with the poorest
prognosis. The conventional treatment includes surgery, radiotherapy, and conventional …

[HTML][HTML] Anaplastic thyroid carcinoma: review of treatment protocols

V Tiedje, M Stuschke, F Weber, H Dralle… - Endocrine-related …, 2018 - erc.bioscientifica.com
Anaplastic thyroid carcinoma (ATC) is an orphan disease and in most patients fatal. So far
no established treatment is available that prolongs survival. Several large retrospective …

Anaplastic thyroid carcinoma: an epidemiologic, histologic, immunohistochemical, and molecular single-institution study

A Deeken-Draisey, GY Yang, J Gao, BA Alexiev - Human pathology, 2018 - Elsevier
Anaplastic thyroid carcinoma (ATC) is a highly aggressive form of thyroid cancer. A single-
institution thyroid cancer cohort of ATC was identified within the last 10 years at our …

[PDF][PDF] Anaplastic thyroid carcinoma: Updates on WHO classification, clinicopathological features and staging

I Abe, K Lam - 2021 - hh.um.es
Anaplastic thyroid carcinoma is an uncommon carcinoma representing 1 to 4% of all thyroid
cancers. The carcinoma is most common in females of the eight decades. It is a locally …

[HTML][HTML] Molecular imaging and theragnostics of thyroid cancers

L Giovanella, D Deandreis, A Vrachimis, A Campenni… - Cancers, 2022 - mdpi.com
Simple Summary According to the American Cancer Society, approximately 53,000 new
cases of thyroid cancer were diagnosed and more than 2200 people died from the disease …

[HTML][HTML] Customizing cancer treatment at the nanoscale: a focus on anaplastic thyroid cancer therapy

J Wang, J Tan, B Wu, R Wu, Y Han, C Wang… - Journal of …, 2023 - Springer
Anaplastic thyroid cancer (ATC) is a rare but highly aggressive kind of thyroid cancer.
Various therapeutic methods have been considered for the treatment of ATC, but its …