New insights into transcriptional reprogramming during cellular stress
SV Himanen, L Sistonen - Journal of cell science, 2019 - journals.biologists.com
Cellular stress triggers reprogramming of transcription, which is required for the
maintenance of homeostasis under adverse growth conditions. Stress-induced changes in …
maintenance of homeostasis under adverse growth conditions. Stress-induced changes in …
Intracellular co-delivery of Sr ion and phenamil drug through mesoporous bioglass nanocarriers synergizes BMP signaling and tissue mineralization
Inducing differentiation and maturation of resident multipotent stem cells (MSCs) is an
important strategy to regenerate hard tissues in mal-calcification conditions. Here we …
important strategy to regenerate hard tissues in mal-calcification conditions. Here we …
Biomimetic copper-doped polypyrrole nanoparticles for enhanced cancer low-temperature photothermal therapy
H Chen, X Luo, W Cai, S Wang, J Xiang… - International Journal of …, 2023 - Taylor & Francis
Introduction Photothermal therapy (PTT) has a significant potential for its application in
precision tumour therapy. However, PTT-induced hyperthermia may damage healthy tissues …
precision tumour therapy. However, PTT-induced hyperthermia may damage healthy tissues …
[HTML][HTML] Selective killing effects of cold atmospheric pressure plasma with NO induced dysfunction of epidermal growth factor receptor in oral squamous cell carcinoma
The aim of this study is to investigate the effects of cold atmospheric pressure plasma (CAP)-
induced radicals on the epidermal growth factor receptor (EGFR), which is overexpressed by …
induced radicals on the epidermal growth factor receptor (EGFR), which is overexpressed by …
[HTML][HTML] The NOR1/OSCP1 proteins in cancer: from epigenetic silencing to functional characterization of a novel tumor suppressor
M Yi, J Yang, W Li, X Li, W Xiong, JB McCarthy… - Journal of …, 2017 - ncbi.nlm.nih.gov
Abstract NOR1 (Oxidored-nitro domain-containing protein 1), also known as OSCP1, was
first identified in nasopharyngeal carcinoma (NPC) cells in 2003. NOR1 is evolutionarily …
first identified in nasopharyngeal carcinoma (NPC) cells in 2003. NOR1 is evolutionarily …
[HTML][HTML] Heat shock factor 1 drives regulatory T-cell induction to limit murine intestinal inflammation
CB Collins, TT Nguyen, RS Leddy, KM Alula… - Mucosal …, 2024 - Elsevier
The heat shock response is a critical component of the inflammatory cascade that prevents
misfolding of new proteins and regulates immune responses. Activation of clusters of …
misfolding of new proteins and regulates immune responses. Activation of clusters of …
[HTML][HTML] Mitochondrial succinate dehydrogenase is involved in stimulus-secretion coupling and endogenous ROS formation in murine beta cells
A Edalat, P Schulte-Mecklenbeck, C Bauer, S Undank… - Diabetologia, 2015 - Springer
Aims/hypothesis Generation of reduction equivalents is a prerequisite for nutrient-stimulated
insulin secretion. Mitochondrial succinate dehydrogenase (SDH) fulfils a dual function with …
insulin secretion. Mitochondrial succinate dehydrogenase (SDH) fulfils a dual function with …
[HTML][HTML] NF‑κB regulates HSF1 and c‑Jun activation in heat stress‑induced intestinal epithelial cell apoptosis
J Li, Y Liu, P Duan, R Yu, Z Gu… - Molecular Medicine …, 2018 - spandidos-publications.com
Heat stress may induce intestinal epithelial cell apoptosis; however, the molecular
mechanisms have not yet been identified. The present study used IEC‑6 rat small intestinal …
mechanisms have not yet been identified. The present study used IEC‑6 rat small intestinal …
Dihydromyricetin ameliorates 3NP-induced behavioral deficits and striatal injury in rats
S Mu, Y Li, B Liu, W Wang, S Chen, J Wu… - Journal of Molecular …, 2016 - Springer
Oxidative stress is closely involved in neurodegenerative diseases. The present study aimed
to examine the effect of anti-oxidant DHM (dihydromyricetin) on 3NP (3-nitropropionic acid) …
to examine the effect of anti-oxidant DHM (dihydromyricetin) on 3NP (3-nitropropionic acid) …
HSP70 desensitizes osteosarcoma cells to baicalein and protects cells from undergoing apoptosis
L Ding, S He, X Sun - Apoptosis, 2014 - Springer
Baicalein is a new drug that has shown promising anti-cancer effects against a broad
spectrum of tumors. However, the potential effect on osteosarcoma cells and the …
spectrum of tumors. However, the potential effect on osteosarcoma cells and the …