The pathophysiology of SARS-CoV-2: A suggested model and therapeutic approach
In this paper, a model is proposed of the pathophysiological processes of COVID-19 starting
from the infection of human type II alveolar epithelial cells (pneumocytes) by SARS-CoV-2 …
from the infection of human type II alveolar epithelial cells (pneumocytes) by SARS-CoV-2 …
[HTML][HTML] Pulmonary interstitial matrix and lung fluid balance from normal to the acutely injured lung
This review analyses the mechanisms by which lung fluid balance is strictly controlled in the
air-blood barrier (ABB). Relatively large trans-endothelial and trans-epithelial Starling …
air-blood barrier (ABB). Relatively large trans-endothelial and trans-epithelial Starling …
[HTML][HTML] Unmatched ventilation and perfusion measured by electrical impedance tomography predicts the outcome of ARDS
E Spinelli, M Kircher, B Stender, I Ottaviani, MC Basile… - Critical Care, 2021 - Springer
Background In acute respiratory distress syndrome (ARDS), non-ventilated perfused regions
coexist with non-perfused ventilated regions within lungs. The number of unmatched regions …
coexist with non-perfused ventilated regions within lungs. The number of unmatched regions …
[HTML][HTML] Advanced respiratory monitoring in COVID-19 patients: use less PEEP!
L Roesthuis, M van den Berg, H van der Hoeven - Critical Care, 2020 - Springer
Methods Respiratory mechanics was assessed in COVID-19 patients admitted to the
Radboud University Nijmegen Medical Center as part of standard patient care. Brief …
Radboud University Nijmegen Medical Center as part of standard patient care. Brief …
Acute respiratory distress syndrome (ARDS) caused by the novel coronavirus disease (COVID-19): a practical comprehensive literature review
F Montenegro, L Unigarro, G Paredes… - Expert review of …, 2021 - Taylor & Francis
Introduction The exponential growth of SARS-CoV-2 virus transmission during the first
months of 2020 has placed substantial pressure on most health systems around the world …
months of 2020 has placed substantial pressure on most health systems around the world …
Lung recruitment in obese patients with acute respiratory distress syndrome
J Fumagalli, RRS Santiago, M Teggia Droghi… - …, 2019 - pubs.asahq.org
Abstract Editor's Perspective What We Already Know about This Topic Obesity increases the
propensity to atelectasis in acute respiratory distress syndrome, but the optimal approach to …
propensity to atelectasis in acute respiratory distress syndrome, but the optimal approach to …
Monitoring lung injury severity and ventilation intensity during mechanical ventilation
Acute respiratory distress syndrome (ARDS) is a severe form of respiratory failure burden by
high hospital mortality. No specific pharmacologic treatment is currently available and its …
high hospital mortality. No specific pharmacologic treatment is currently available and its …
Respiratory muscle effort during expiration in successful and failed weaning from mechanical ventilation
J Doorduin, LH Roesthuis, D Jansen… - …, 2018 - pubs.asahq.org
Abstract What We Already Know about This Topic Inspiratory muscle weakness delays
weaning from mechanical ventilation, but the contributions of expiratory muscles activity are …
weaning from mechanical ventilation, but the contributions of expiratory muscles activity are …
Applying Precision Medicine to Trial Design Using Physiology. Extracorporeal CO2 Removal for Acute Respiratory Distress Syndrome
In clinical trials of therapies for acute respiratory distress syndrome (ARDS), the average
treatment effect in the study population may be attenuated because individual patient …
treatment effect in the study population may be attenuated because individual patient …
[HTML][HTML] Effect of body position on the redistribution of regional lung aeration during invasive and non-invasive ventilation of COVID-19 patients
Severe COVID-19-related acute respiratory distress syndrome (C-ARDS) requires
mechanical ventilation. While this intervention is often performed in the prone position to …
mechanical ventilation. While this intervention is often performed in the prone position to …