The impact of ACE and ACE2 gene polymorphisms in pulmonary diseases including COVID-19

I Gintoni, M Adamopoulou, C Yapijakis - in vivo, 2022 - iv.iiarjournals.org
Chronic and acute respiratory diseases pose a major problem for public health worldwide
due to the high morbidity and mortality rates, while treatment options remain mostly …

Role and interaction between ACE1, ACE2 and their related genes in cardiovascular disorders

S Bhushan, Z Xiao, K Gao, L Mao, J Chen… - Current Problems in …, 2023 - Elsevier
Cardiovascular disease is the greatest health care burden and one of the most common
causes of death worldwide. Less is known about the genetic factors that are responsible for …

Local bone marrow renin–angiotensin system in primitive, definitive and neoplastic haematopoiesis

IC Haznedaroglu, Y Beyazit - Clinical science, 2013 - portlandpress.com
The locally active ligand peptides, mediators, receptors and signalling pathways of the
haematopoietic BM (bone marrow) autocrine/paracrine RAS (renin–angiotensin system) …

Renin angiotensin system and its role in biomarkers and treatment in gliomas

A Perdomo-Pantoja, SI Mejía-Pérez… - Journal of neuro …, 2018 - Springer
Gliomas are the most common primary intrinsic tumor in the brain and are classified as low-
or high-grade according to the World Health Organization (WHO). Patients with high-grade …

ACE I/D sequence variants but not MTHFR C677T, is strongly linked to malignant glioma risk and its variant DD genotype may act as a promising predictive biomarker …

AA Pandith, I Qasim, W Zahoor, P Shah, AR Bhat - Gene, 2018 - Elsevier
Abstract Objective ACE I/D and MTHFR C677T gene polymorphisms can be seen as
candidate genes for glioma on the basis of their biological functions and their involvement in …

Association of eNOS and ACE gene polymorphisms and plasma nitric oxide with risk of non‐small cell lung cancer in South India

V Peddireddy, SP Badabagni… - The clinical …, 2018 - Wiley Online Library
Introduction The role of ACE and eNOS gene polymorphisms and their association with
various cancers were reported. However, their role in the lung cancer is unclear. Objectives …

Association between the ACE-I/D polymorphism and nicotine dependence amongst patients with lung cancer

S Nadalin, V Flego, SD Pavlić… - Biomedical …, 2020 - spandidos-publications.com
The biologically active peptide angiotensin II is cleaved from angiotensinogen by the renin
and the angiotensin-converting enzyme (ACE), an enzymatic cascade known as the renin …

[HTML][HTML] Angiotensin-converting enzyme insertion/deletion gene polymorphism in patients with laryngeal cancer

YÇ Kumbul, KH Öztürk, H Yasan, V Akın… - Acta …, 2023 - ncbi.nlm.nih.gov
Objectives The aim of this study was to compare the distribution of the angiotensin-
converting enzyme (ACE) I/D polymorphism between patients with laryngeal cancer (LC) …

[HTML][HTML] Angiotensin-converting enzyme gene deletion polymorphism is associated with lymph node metastasis in colorectal cancer patients in a Chinese population

X Zheng, G Liu, G Cui, M Cheng… - … Medical Journal of …, 2017 - ncbi.nlm.nih.gov
Angiotensin-Converting Enzyme Gene Deletion Polymorphism is Associated with Lymph
Node Metastasis in Colorectal Cancer Patients in a Chinese Population - PMC Back to Top …

Contribution of Endothelial Dysfunction to Cancer Susceptibility and Progression: A Comprehensive Narrative Review on the Genetic Risk Component

IG de Melo, V Tavares, D Pereira… - Current Issues in Molecular …, 2024 - mdpi.com
Venous thromboembolism (VTE) is a challenging clinical obstacle in oncological settings,
marked by elevated incidence rates and resulting morbidity and mortality. In the context of …