Clinical outcomes of parenchymal-sparing versus anatomic resection for colorectal liver metastases: a systematic review and meta-analysis

K Wang, Y Liu, M Hao, H Li, X Liang, D Yuan… - World Journal of Surgical …, 2023 - Springer
Background The advantages of parenchymal-sparing resection (PSR) over anatomic
resection (AR) of colorectal liver metastases (CRLM) remain controversial. Here, we aim to …

The management of colorectal liver metastases amenable of surgical resection: How to shape treatment strategies according to clinical, radiological, pathological and …

MM Germani, B Borelli, P Boraschi, C Antoniotti… - Cancer Treatment …, 2022 - Elsevier
Metastatic colorectal cancer (mCRC) patients have poor chances of long term survival,
being< 15% of them still alive after 5 years from diagnosis. Nonetheless, patients with …

Neither surgical margin status nor somatic mutation predicts local recurrence after R0-intent resection for colorectal liver metastases

Y Nishioka, N Paez-Arango, FO Boettcher… - Journal of …, 2022 - Elsevier
Background We evaluated the associations of surgical margin status and somatic mutations
with the incidence of local recurrence (LR) and oncologic outcomes in patients undergoing …

ICG-Fluorescence Imaging for Margin Assessment During Minimally Invasive Colorectal Liver Metastasis Resection

FB Achterberg, OD Bijlstra, MD Slooter… - JAMA network …, 2024 - jamanetwork.com
Importance Unintended tumor-positive resection margins occur frequently during minimally
invasive surgery for colorectal liver metastases and potentially negatively influence …

[HTML][HTML] Parenchymal-sparing hepatectomy for colorectal liver metastases reduces postoperative morbidity while maintaining equivalent oncologic outcomes …

A Andreou, S Gloor, J Inglin, CDP Martinelli, V Banz… - Surgical oncology, 2021 - Elsevier
Background Modern chemotherapy and repeat hepatectomy allow to tailor the surgical
strategies for the treatment of colorectal liver metastases (CRLM). This study addresses the …

Tumor biology reflected by histological growth pattern is more important than surgical margin for the prognosis of patients undergoing resection of colorectal liver …

A Bohlok, L Inchiostro, V Lucidi, S Vankerckhove… - European Journal of …, 2023 - Elsevier
Introduction The histological growth pattern (HGP) of colorectal liver metastases (CRLMs)
reflects tumor biology and local infiltrating behavior. In patients undergoing surgery for …

Role of preoperative 3D rendering for minimally invasive parenchyma sparing liver resections

R Montalti, G Rompianesi, G Cassese, F Pegoraro… - HPB, 2023 - Elsevier
Abstract Background 3D rendering (3DR) represents a promising approach to plan surgical
strategies. The study aimed to compare the results of minimally invasive liver resections …

Objective definition and optimized strategy for “biologically borderline resectable” colorectal liver metastases

T Takamoto, S Nara, D Ban, T Mizui, Y Murase… - World Journal of …, 2023 - Springer
Background The prognostic benefit of preoperative chemotherapy leading to conversion
surgery for unresectable colorectal liver metastases (CRLM) is well recognized, while that of …

Targeted exome-based predictors of patterns of progression of colorectal liver metastasis after percutaneous thermal ablation

I Paolucci, YM Lin, Y Kawaguchi, H Maki… - British journal of …, 2023 - nature.com
Background Percutaneous thermal ablation is a curative-intent locoregional therapy (LRT)
for selected patients with unresectable colorectal liver metastasis (CLM). Several factors …

Prognostic impact of R1 resection margin in synchronous and simultaneous colorectal liver metastasis resection: a retrospective cohort study

NR Kim, ED Alhothaifi, DH Han, JS Choi… - World journal of surgical …, 2023 - Springer
Background A margin≥ 1 mm is considered a standard resection margin for colorectal liver
metastasis (CRLM). However, microscopic incomplete resection (R1) is not rare since …