Preservation and storage stability of extracellular vesicles for therapeutic applications

A Jeyaram, SM Jay - The AAPS journal, 2018 - Springer
Abstract Recently, extracellular vesicles (EVs)—including exosomes, microvesicles, and
others—have attracted interest as cell-derived biotherapeutics and drug delivery vehicles for …

[HTML][HTML] Mesenchymal stromal/stem cell-derived extracellular vesicles in tissue repair: challenges and opportunities

S Varderidou-Minasian, MJ Lorenowicz - Theranostics, 2020 - ncbi.nlm.nih.gov
Mesenchymal stem/stromal cells (MSCs) are important players in tissue homeostasis and
regeneration owing to their immunomodulatory potential and release of trophic factors that …

RAB31 marks and controls an ESCRT-independent exosome pathway

D Wei, W Zhan, Y Gao, L Huang, R Gong, W Wang… - Cell research, 2021 - nature.com
Exosomes are generated within the multivesicular endosomes (MVEs) as intraluminal
vesicles (ILVs) and secreted during the fusion of MVEs with the cell membrane. The …

Extracellular vesicles from human plasma and serum are carriers of extravesicular cargo—Implications for biomarker discovery

M Palviainen, M Saraswat, Z Varga, D Kitka… - PloS one, 2020 - journals.plos.org
Extracellular vesicles (EVs) in human blood are a potential source of biomarkers. To which
extent anticoagulation affects their concentration, cellular origin and protein composition is …

[HTML][HTML] Therapeutic potential of exosome‐based personalized delivery platform in chronic inflammatory diseases

C Wang, M Xu, Q Fan, C Li, X Zhou - Asian journal of pharmaceutical …, 2023 - Elsevier
In the inflammatory microenvironment, there are numerous exosomes secreted by immune
cells (Macrophages, neutrophils, dendritic cells), mesenchymal stem cells (MSCs) and …

Hypoxia Conditioned Mesenchymal Stem Cell-Derived Extracellular Vesicles Induce Increased Vascular Tube Formation in vitro

C Almeria, R Weiss, M Roy, C Tripisciano… - … in Bioengineering and …, 2019 - frontiersin.org
Mesenchymal stem/stromal cells (MSCs) display a variety of therapeutically relevant effects,
such as the induction of angiogenesis, particularly under hypoxic conditions. It is generally …

Extracellular microvesicles as new industrial therapeutic frontiers

V Agrahari, V Agrahari, PA Burnouf, CH Chew… - Trends in …, 2019 - cell.com
Microvesicles (MVs) are subcellular physiological vehicles present in all body fluids that
mediate the transfer of intercellular information within biological systems and contribute to …

Advances in exosomes technology

BY Chen, CWH Sung, C Chen, CM Cheng, DPC Lin… - Clinica chimica acta, 2019 - Elsevier
Exosomes, also called extracellular vesicles (EVs), are membranous structures measuring
between 40 and 100 nm. Exosomes, secreted by various cells of the human body into body …

[HTML][HTML] Exosomes and their bioengineering strategies in the cutaneous wound healing and related complications: current knowledge and future perspectives

G Yang, S Waheed, C Wang, M Shekh… - International Journal of …, 2023 - ncbi.nlm.nih.gov
Exosomes, as therapeutically relevant cell-secreted extracellular vesicles, have attracted
enormous interest because they participate in intercellular communication and facilitate …

Exosomal non-coding RNAs: new insights into the biology of hepatocellular carcinoma

Q Zhang, H Li, Y Liu, J Li, C Wu, H Tang - Current Oncology, 2022 - mdpi.com
Exosomes, extracellular vesicles with a diameter of 40 to 160 nm, are among the smallest
extracellular vesicles released by cells. They deliver different cargoes, including proteins …