Objective: To attempt to determine the relative value of preclinical cardiac electrophysiology
data (in vitro and in vivo) for predicting risk of torsade de pointes (TdP) in clinical use …

Cardiotoxicity, defined as toxicity that affects the heart, is one of the most common adverse
drug effects. Numerous drugs have been shown to have the potential to induce lethal …

The pharmacological treatment of urinary incontinence Page 1 BJU International (1999), 84,
923–947 REVIEW The pharmacological treatment of urinary incontinence K.-E …

The old saying 'red as a beet, dry as a bone, blind as a bat, hot as a hare, mad as a hatter'is
often quoted when describing the autonomic effects of drugs that block the muscarinic …

Numerous medications, including drugs prescribed for noncardiac indications, can lead to
QT prolongation and trigger torsade de pointes. Although this complication occurs only …

The incidence of drug-induced proarrhythmias in the general population is largely unknown.
Knowledge regarding incidence and risk factors is mainly derived from studies during …

Background: Evidence has accrued that several non-cardiac drugs may prolong cardiac
repolarisation (hence, the QT interval of the surface electrocardiogram) to such a degree that …

Pharmacological treatment of overactive bladder: report from... : Current Opinion in Urology
Pharmacological treatment of overactive bladder: report from the International Consultation on …

Background: The growing list of non-antiarrhythmic drugs associated with QT prolongation
and the relevant regulatory interventions have generated concern for two reasons. First, QT …

Objectives To assess the prevalence of and risk factors for urinary (UI) and fecal (FI)
incontinence in adults in long-term care (LTC) settings and in the community, the …