Simple Summary By delivering escalated doses to biologically defined sub-volumes within a
target, focal boost radiotherapy is expected to enable an elevated tumor control without an …

Purpose: Focal therapy has been proposed as an alternative method to whole‐gland
treatment for prostate cancer when aiming to reduce treatment side effects. The authors …

Histopathological analysis of Whole Slide Images (WSIs) has seen a surge in the utilization
of deep learning methods, particularly Convolutional Neural Networks (CNNs). However …

Background: There are currently no methods to estimate cell density in the prostate. This
study aimed to develop predictive models to estimate prostate cell density from …

Background In prostate radiation therapy, recent studies have indicated a benefit in
increasing the dose to intraprostatic lesions (IPL) compared with standard whole gland …

Background and purpose Radiation therapy (RT) is commonly indicated for treatment of
prostate cancer (PC). Biologicallyoptimised RT for PC may improve disease-free survival …

Classification of prostate tumor regions in digital histology images requires comparable
features across datasets. Here we introduce adaptive cell density estimation and apply H&E …

Reliable automated prostate tumor detection and characterization in whole-mount histology
images is sought in many applications, including post-resection tumor staging and as …

Breast cancer is a common disease and the diagnosis as well as treatment decisions are
among other factors largely based on a number of examinations by the pathologist. They are …

Purpose We describe a novel approach to treatment planning for focal brachytherapy
utilizing a biologically based inverse optimization algorithm and biological imaging to target …