Systematic review: the gut microbiome and its potential clinical application in inflammatory bowel disease

L Aldars-Garcia, M Chaparro, JP Gisbert - Microorganisms, 2021 - mdpi.com
Inflammatory bowel disease (IBD) is a chronic relapsing–remitting systemic disease of the
gastrointestinal tract. It is well established that the gut microbiome has a profound impact on …

Computational analysis of microbial flow cytometry data

P Rubbens, R Props - MSystems, 2021 - Am Soc Microbiol
Flow cytometry is an important technology for the study of microbial communities. It grants
the ability to rapidly generate phenotypic single-cell data that are both quantitative …

Opportunities in optical and electrical single-cell technologies to study microbial ecosystems

F Mermans, V Mattelin, R Van den Eeckhoudt… - Frontiers in …, 2023 - frontiersin.org
New techniques are revolutionizing single-cell research, allowing us to study microbes at
unprecedented scales and in unparalleled depth. This review highlights the state-of-the-art …

PhenoGMM: Gaussian mixture modeling of cytometry data quantifies changes in microbial community structure

P Rubbens, R Props, FM Kerckhof, N Boon… - MSphere, 2021 - Am Soc Microbiol
Microbial flow cytometry can rapidly characterize the status of microbial communities. Upon
measurement, large amounts of quantitative single-cell data are generated, which need to …

[HTML][HTML] Recent advances in microbial community analysis from machine learning of multiparametric flow cytometry data

BDÖ Duygan, JR van der Meer - Current Opinion in Biotechnology, 2022 - Elsevier
Highlights•Large multiparametric flow cytometry data sets are ideal for machine learning.•
Unsupervised clustering methods highlight microbial community changes.•Supervised …

Exploration of microbiome diversity of stacked fermented grains by flow cytometry and cell sorting

Z Zhang, Y Wei, Z Peng, P Du, X Du, G Zuo… - Frontiers in …, 2023 - frontiersin.org
Sauce-flavor baijiu is one of the twelve flavor types of Chinese distilled fermented product.
Microbial composition plays a key role in the stacked fermentation of Baijiu, which uses …

Gut microbiota-modulated metabolomic profiling shapes the etiology and pathogenesis of autoimmune diseases

YW Tsai, JL Dong, YJ Jian, SH Fu, MW Chien, YW Liu… - Microorganisms, 2021 - mdpi.com
Autoimmunity is a complex and multifaceted process that contributes to widespread
functional decline that affects multiple organs and tissues. The pandemic of autoimmune …

Fast quantification of gut bacterial species in cocultures using flow cytometry and supervised classification

CC van de Velde, C Joseph, A Biclot… - ISME …, 2022 - academic.oup.com
A bottleneck for microbial community experiments with many samples and/or replicates is
the fast quantification of individual taxon abundances, which is commonly achieved through …

Emerging investigator series: optimisation of drinking water biofilm cell detachment and sample homogenisation methods for rapid quantification via flow cytometry

FC Pick, KE Fish - Environmental Science: Water Research & …, 2024 - pubs.rsc.org
Understanding biofilm microbial loads and viability within drinking water pipes is critical to
inform sustainable management of ageing infrastructure to protect future water quality. This …

Predicting the presence and abundance of bacterial taxa in environmental communities through flow cytometric fingerprinting

J Heyse, F Schattenberg, P Rubbens, S Müller… - Msystems, 2021 - Am Soc Microbiol
Microbiome management research and applications rely on temporally resolved
measurements of community composition. Current technologies to assess community …