Characterizing DNA methylation signatures of retinoblastoma using aqueous humor liquid biopsy
Retinoblastoma (RB) is a cancer that forms in the developing retina of babies and toddlers.
The goal of therapy is to cure the tumor, save the eye and maximize vision. However, it is …
The goal of therapy is to cure the tumor, save the eye and maximize vision. However, it is …
Proteomics of aqueous humor as a source of disease biomarkers in retinoblastoma
A Galardi, C Stathopoulos, M Colletti… - International Journal of …, 2022 - mdpi.com
Aqueous humor (AH) can be easily and safely used to evaluate disease-specific biomarkers
in ocular disease. The aim of this study was to identify specific proteins biomarkers in the AH …
in ocular disease. The aim of this study was to identify specific proteins biomarkers in the AH …
Trefoil Family Factor Peptide 1—A New Biomarker in Liquid Biopsies of Retinoblastoma under Therapy
MA Busch, A Haase, E Alefeld, E Biewald, L Jabbarli… - Cancers, 2023 - mdpi.com
Simple Summary Effective management of retinoblastoma (RB), a common childhood eye
cancer, requires accurate diagnosis and monitoring during therapy. In this study, the liquid …
cancer, requires accurate diagnosis and monitoring during therapy. In this study, the liquid …
AHP DB: a reference database of proteins in the human aqueous humor
The aqueous humor (AH) is a low-viscosity biofluid that continuously circulates from the
posterior chamber to the anterior chamber of the eye. Recent advances in high-resolution …
posterior chamber to the anterior chamber of the eye. Recent advances in high-resolution …
PDGF, NGF, and EGF as main contributors to tumorigenesis in high-risk retinoblastoma
K Al-Ghazzawi, M Wessolly, S Dalbah, P Ketteler… - Frontiers in …, 2023 - frontiersin.org
Retinoblastoma (RB) is the most common form of eye cancer experienced in childhood. Its
aggressive malignancy is associated with excellent survival rates in high-income countries; …
aggressive malignancy is associated with excellent survival rates in high-income countries; …
Aqueous Humor Liquid Biopsy as a Companion Diagnostic for Retinoblastoma: implications for diagnosis, prognosis and therapeutic options. Five years of Progress
ABSTRACT PURPOSE To describe the prospective use of the aqueous humor (AH) as a
molecular diagnostic and prognostic liquid biopsy for retinoblastoma (RB). METHODS …
molecular diagnostic and prognostic liquid biopsy for retinoblastoma (RB). METHODS …
[HTML][HTML] A multicenter analysis of nucleic acid quantification using aqueous humor liquid biopsy in retinoblastoma: implications for clinical testing
DH Im, S Pike, MW Reid, CC Peng, S Sirivolu… - Ophthalmology …, 2023 - Elsevier
Purpose Retinoblastoma (RB) is most often diagnosed with clinical features and not
diagnosed with tumor biopsy. This study describes tumor-derived analyte concentrations …
diagnosed with tumor biopsy. This study describes tumor-derived analyte concentrations …
Immunohistochemical expression of TFF1 is a marker of poor prognosis in retinoblastoma
R Aschero, D Ganiewich, G Lamas… - Pediatric Blood & …, 2024 - Wiley Online Library
Introduction The risk of relapse in retinoblastoma is currently determined by the presence of
high‐risk histopathologic factors in the enucleated eye. However, the probability of …
high‐risk histopathologic factors in the enucleated eye. However, the probability of …
[HTML][HTML] The potential of aqueous humor sampling in diagnosis, prognosis, and treatment of retinoblastoma
A Muniyandi, NR Jensen, N Devanathan… - … & Visual Science, 2024 - tvst.arvojournals.org
Retinoblastoma (RB) is a rare malignant tumor that arises in the developing retina in one or
both eyes of children. Pathogenic variants of the RB1 tumor suppressor gene drive the …
both eyes of children. Pathogenic variants of the RB1 tumor suppressor gene drive the …
Gastric Inhibitory Polypeptide Receptor (GIPR) Overexpression Reduces the Tumorigenic Potential of Retinoblastoma Cells
A Haase, E Alefeld, F Yalinci, DV Meenen, MA Busch… - Cancers, 2024 - mdpi.com
Simple Summary Retinoblastoma (RB) is a malignant childhood eye cancer. In search for
new or adjuvant treatment options, the gastric inhibitory polypeptide receptor (GIPR) …
new or adjuvant treatment options, the gastric inhibitory polypeptide receptor (GIPR) …