The mucosal lining of the gut has co-evolved with a diverse microbiota over millions of
years, leading to the development of specialized mechanisms to actively limit the invasion of …

The Wnt/β-catenin signaling pathway is crucial to regulate cell proliferation and polarity, cell
determination, and tissue homeostasis. The activation of Wnt/β-catenin signaling is based …

In order to survive and replicate, Salmonella has evolved mechanisms to gain access to
intestinal epithelial cells of the crypt. However, the impact of Salmonella Typhimurium on …

Human milk oligosaccharides (HMOs) are an evolutionarily significant advantage bestowed
by mothers for facilitating the development of the infant's gut microbiota. They can avoid …

Lawsonia intracellularis is an anaerobic obligate intracellular bacterium infecting the small
intestine and infrequently also the large intestine of pigs and other animals including …

Antimicrobial agents and alternative strategies to combat bacterial infections have become
urgent due to the rapid development of multidrug-resistant bacteria caused by the misuse …

The intestine serves mainly as a place for digestion and absorption and functions as an
immune and endocrine organ. Intestinal stem cells (ISCs) play critical roles in the …

Aggression is a complex social behavior, critically involving brain serotonin (5-HT) function.
The neurobiology of female aggression remains elusive, while the incidence of its …

Porcine proliferative ileitis is a major economic burden for the swine industry, affecting
growing pigs and young adult pigs. In this study, the protective efficacy of an inactivated …

Infection research largely relies on classical cell culture or mouse models. Despite having
delivered invaluable insights into host-pathogen interactions, both have limitations in …