Neutrophil heterogeneity in cancer: from biology to therapies
P Lecot, M Sarabi, M Pereira Abrantes… - Frontiers in …, 2019 - frontiersin.org
Neutrophils have been extensively described in the pathophysiology of autoimmune and
infectious diseases. Accumulating evidence also suggests the important role of neutrophils …
infectious diseases. Accumulating evidence also suggests the important role of neutrophils …
Dual roles of neutrophils in metastatic colonization are governed by the host NK cell status
The role of neutrophils in solid tumor metastasis remains largely controversial. In preclinical
models of solid tumors, both pro-metastatic and anti-metastatic effects of neutrophils have …
models of solid tumors, both pro-metastatic and anti-metastatic effects of neutrophils have …
Significance of tumor mutation burden in immune infiltration and prognosis in cutaneous melanoma
K Kang, F Xie, J Mao, Y Bai, X Wang - Frontiers in oncology, 2020 - frontiersin.org
Background: Melanoma is highly immunogenic and therefore suitable for immunotherapy,
but the efficacy is limited by response rate. In several types of tumor, tumor mutation burden …
but the efficacy is limited by response rate. In several types of tumor, tumor mutation burden …
Neutrophil-to-lymphocyte ratio as a predictive marker of metabolic syndrome
CC Liu, HJ Ko, WS Liu, CL Hung, KC Hu, LY Yu… - Medicine, 2019 - journals.lww.com
Neutrophil-to-lymphocyte ratio (NLR) serves as a strong prognostic indicator for patients
suffering from various diseases. Neutrophil activation promotes the recruitment of a number …
suffering from various diseases. Neutrophil activation promotes the recruitment of a number …
Is the neutrophil-to-lymphocyte ratio a useful prognostic indicator in melanoma patients?
JT Cohen, TJ Miner, MP Vezeridis - Melanoma management, 2020 - Taylor & Francis
The neutrophil-to-lymphocyte ratio (NLR) is gaining traction as a biomarker with utility in a
variety of malignancies including melanoma. Intact lymphocyte function is necessary for …
variety of malignancies including melanoma. Intact lymphocyte function is necessary for …
High neutrophil‐to‐lymphocyte ratio (NLR) is associated with treatment failure and death in patients who have melanoma treated with PD‐1 inhibitor monotherapy
EK Bartlett, JR Flynn, KS Panageas, RA Ferraro… - Cancer, 2020 - Wiley Online Library
Background An elevated neutrophil‐to‐lymphocyte ratio (NLR) is associated with poor
survival in patients with cancer, including those who receive immunotherapies. The authors …
survival in patients with cancer, including those who receive immunotherapies. The authors …
Systemic immune‐inflammation index (SII) is useful to predict survival outcomes in patients with surgically resected non‐small cell lung cancer
Background The systemic immune‐inflammation index (SII) is correlated with patient
survival in various types of solid tumors. However, only a few studies have focused on the …
survival in various types of solid tumors. However, only a few studies have focused on the …
The MLR, NLR, PLR and D-dimer are associated with clinical outcome in lung cancer patients treated with surgery
J Wang, H Li, R Xu, T Lu, J Zhao, P Zhang, L Qu… - BMC pulmonary …, 2022 - Springer
Objective The study objective was to investigate the use of peripheral blood biomarkers as
predictors of patient survival. The aim of this study was to identify the baseline peripheral …
predictors of patient survival. The aim of this study was to identify the baseline peripheral …
TimiGP: Inferring cell-cell interactions and prognostic associations in the tumor immune microenvironment through gene pairs
Determining the prognostic association of different immune cell types in the tumor
microenvironment is critical for understanding cancer biology and developing new …
microenvironment is critical for understanding cancer biology and developing new …
Prognostic value of systemic inflammatory markers for oral cancer patients based on the 8th edition of AJCC staging system
It has been recognized that systemic inflammatory markers (SIMs) are associated with
patient survival in various types of cancer. This study aimed to determine the optimal cut-off …
patient survival in various types of cancer. This study aimed to determine the optimal cut-off …