Consensus criteria for diagnosis, staging, and treatment response assessment of T-cell prolymphocytic leukemia
T-cell prolymphocytic leukemia (T-PLL) is a rare, mature T-cell neoplasm with a
heterogeneous clinical course. With the advent of novel treatment options that will potentially …
heterogeneous clinical course. With the advent of novel treatment options that will potentially …
Leukemia cutis
JH Cho-Vega, LJ Medeiros, VG Prieto… - American journal of …, 2008 - academic.oup.com
Leukemia cutis (LC) is a nonspecific term used for cutaneous manifestations of any type of
leukemia. LC has a wide range of cutaneous manifestations, which can make it difficult to …
leukemia. LC has a wide range of cutaneous manifestations, which can make it difficult to …
EuroFlow antibody panels for standardized n-dimensional flow cytometric immunophenotyping of normal, reactive and malignant leukocytes
JJM Van Dongen, L Lhermitte, S Böttcher, J Almeida… - Leukemia, 2012 - nature.com
Most consensus leukemia & lymphoma antibody panels consist of lists of markers based on
expert opinions, but they have not been validated. Here we present the validated EuroFlow …
expert opinions, but they have not been validated. Here we present the validated EuroFlow …
Blocking STAT3/5 through direct or upstream kinase targeting in leukemic cutaneous T‐cell lymphoma
H Sorger, S Dey, PA Vieyra‐Garcia… - EMBO Molecular …, 2022 - embopress.org
Leukemic cutaneous T‐cell lymphomas (L‐CTCL) are lymphoproliferative disorders of skin‐
homing mature T‐cells causing severe symptoms and high mortality through chronic …
homing mature T‐cells causing severe symptoms and high mortality through chronic …
Actionable perturbations of damage responses by TCL1/ATM and epigenetic lesions form the basis of T-PLL
A Schrader, G Crispatzu, S Oberbeck, P Mayer… - Nature …, 2018 - nature.com
T-cell prolymphocytic leukemia (T-PLL) is a rare and poor-prognostic mature T-cell
malignancy. Here we integrated large-scale profiling data of alterations in gene expression …
malignancy. Here we integrated large-scale profiling data of alterations in gene expression …
Evolution of slow-binding inhibitors targeting histone deacetylase isoforms
Because the overexpression of histone deacetylase enzymes (HDACs) has been linked to
numerous diseases, including various cancers and neurodegenerative disorders, HDAC …
numerous diseases, including various cancers and neurodegenerative disorders, HDAC …
TET2 mutations, myelodysplastic features, and a distinct immunoprofile characterize blastic plasmacytoid dendritic cell neoplasm in the bone marrow
K Alayed, KP Patel, S Konoplev… - American journal of …, 2013 - Wiley Online Library
Distinguishing blastic plasmacytoid dendritic cell neoplasm (BPDCN) from acute myeloid
leukemia (AML) is gaining increased importance because of emerging differences in …
leukemia (AML) is gaining increased importance because of emerging differences in …
TCL1 shows a regulated expression pattern in chronic lymphocytic leukemia that correlates with molecular subtypes and proliferative state
Expression of the human oncogene TCL1 in transgenic mice produces B-cell tumors that
resemble chronic lymphocytic leukemia (CLL) suggesting its role in B-cell tumorigenesis. To …
resemble chronic lymphocytic leukemia (CLL) suggesting its role in B-cell tumorigenesis. To …
Discovery of novel drug sensitivities in T-PLL by high-throughput ex vivo drug testing and mutation profiling
T-cell prolymphocytic leukemia (T-PLL) is a rare and aggressive neoplasm of mature T-cells
with an urgent need for rationally designed therapies to address its notoriously chemo …
with an urgent need for rationally designed therapies to address its notoriously chemo …
CD4+/CD56+ hematodermic tumor: the features of an evolving entity and its relationship to dendritic cells
Described herein is the evolution in the diagnosis and classification of tumors that are
variously known as blastic or blastoid natural killer cell lymphoma, CD4+/CD56+ …
variously known as blastic or blastoid natural killer cell lymphoma, CD4+/CD56+ …