Organelle-targeted therapies: a comprehensive review on system design for enabling precision oncology
Cancer is a major threat to human health. Among various treatment methods, precision
therapy has received significant attention since the inception, due to its ability to efficiently …
therapy has received significant attention since the inception, due to its ability to efficiently …
The importance of the omega-6/omega-3 fatty acid ratio in cardiovascular disease and other chronic diseases
AP Simopoulos - Experimental biology and medicine, 2008 - journals.sagepub.com
Several sources of information suggest that human beings evolved on a diet with a ratio of
omega-6 to omega-3 essential fatty acids (EFA) of~ 1 whereas in Western diets the ratio is …
omega-6 to omega-3 essential fatty acids (EFA) of~ 1 whereas in Western diets the ratio is …
Alpha‐linolenic acid: an omega‐3 fatty acid with neuroprotective properties—ready for use in the stroke clinic?
Alpha‐linolenic acid (ALA) is plant‐based essential omega‐3 polyunsaturated fatty acids
that must be obtained through the diet. This could explain in part why the severe deficiency …
that must be obtained through the diet. This could explain in part why the severe deficiency …
Peroxisome metabolism in cancer
JA Kim - Cells, 2020 - mdpi.com
Peroxisomes are metabolic organelles involved in lipid metabolism and cellular redox
balance. Peroxisomal function is central to fatty acid oxidation, ether phospholipid synthesis …
balance. Peroxisomal function is central to fatty acid oxidation, ether phospholipid synthesis …
[PDF][PDF] The omega-6/omega-3 fatty acid ratio, genetic variation, and cardiovascular disease.
AP Simopoulos - Asia Pacific journal of clinical nutrition, 2008 - apjcn.nhri.org.tw
A high omega-6/omega-3 ratio, as is found in today's Western diets, promotes the
pathogenesis of many chronic diseases, including cardiovascular disease. Increased dietary …
pathogenesis of many chronic diseases, including cardiovascular disease. Increased dietary …
Evolutionary aspects of the dietary omega-6/omega-3 fatty acid ratio: medical implications
AP Simopoulos - Evolutionary Thinking in Medicine: From Research to …, 2016 - Springer
Several sources of information suggest that humans evolved on a diet with an equal ratio of
omega-6 (ω-6) to omega-3 (ω-3) fatty acids, whereas in today's Western diet, this ratio is …
omega-6 (ω-6) to omega-3 (ω-3) fatty acids, whereas in today's Western diet, this ratio is …
COVID-19. Pandemic surgery guidance
Based on high quality surgery and scientific data, scientists and surgeons are committed to
protecting patients as well as healthcare staff and hereby provide this Guidance to address …
protecting patients as well as healthcare staff and hereby provide this Guidance to address …
EISA in tandem with ICD to form in situ nanofiber vaccine for enhanced tumor radioimmunotherapy
H Luo, H Cao, H Jia, Y Shang, J Liu… - Advanced …, 2023 - Wiley Online Library
Radiotherapy (RT) can produce a vaccine effect and remodel a tumor microenvironment
(TME) by inducing immunogenic cell death (ICD) and inflammation in tumors. However, RT …
(TME) by inducing immunogenic cell death (ICD) and inflammation in tumors. However, RT …
Promotion of prostatic metastatic migration towards human bone marrow stoma by Omega 6 and its inhibition by Omega 3 PUFAs
MD Brown, CA Hart, E Gazi, S Bagley… - British journal of …, 2006 - nature.com
Epidemiological studies have shown not only a relationship between the intake of dietary
lipids and an increased risk of developing metastatic prostate cancer, but also the type of …
lipids and an increased risk of developing metastatic prostate cancer, but also the type of …
Arachidonic acid activates phosphatidylinositol 3-kinase signaling and induces gene expression in prostate cancer
M Hughes-Fulford, CF Li, J Boonyaratanakornkit… - Cancer Research, 2006 - AACR
Essential fatty acids are not only energy-rich molecules; they are also an important
component of the membrane bilayer and recently have been implicated in induction of fatty …
component of the membrane bilayer and recently have been implicated in induction of fatty …