Biological control of plant diseases–What has been achieved and what is the direction?

DB Collinge, DF Jensen, M Rabiey, S Sarrocco… - Plant …, 2022 - Wiley Online Library
The global sustainability agenda is increasing the demand for reduction in inputs into
agricultural production while maintaining profitable yield of quality products. Plant diseases …

[HTML][HTML] Emerging strategies to combat ESKAPE pathogens in the era of antimicrobial resistance: a review

MS Mulani, EE Kamble, SN Kumkar… - Frontiers in …, 2019 - frontiersin.org
The acronym ESKAPE includes six nosocomial pathogens that exhibit multidrug resistance
and virulence: Enterococcus faecium, Staphylococcus aureus, Klebsiella pneumoniae …

Current challenges and future opportunities of phage therapy

DP Pires, AR Costa, G Pinto, L Meneses… - FEMS microbiology …, 2020 - academic.oup.com
Antibiotic resistance is a major public health challenge worldwide, whose implications for
global health might be devastating if novel antibacterial strategies are not quickly …

Phage therapy: What factors shape phage pharmacokinetics and bioavailability? Systematic and critical review

K Dąbrowska - Medicinal research reviews, 2019 - Wiley Online Library
Bacteriophages are not forgotten viruses anymore: scientists and practitioners seek to
understand phage pharmacokinetics in animals and humans, investigating bacteriophages …

[HTML][HTML] Engineered bacteriophage therapeutics: rationale, challenges and future

M Łobocka, K Dąbrowska, A Górski - BioDrugs, 2021 - Springer
The current problems with increasing bacterial resistance to antibacterial therapies, resulting
in a growing frequency of incurable bacterial infections, necessitates the acceleration of …

Pharmacologically aware phage therapy: pharmacodynamic and pharmacokinetic obstacles to phage antibacterial action in animal and human bodies

K Dąbrowska, ST Abedon - Microbiology and Molecular Biology …, 2019 - Am Soc Microbiol
The use of viruses infecting bacteria (bacteriophages or phages) to treat bacterial infections
has been ongoing clinically for approximately 100 years. Despite that long history, the …

[HTML][HTML] Recent advances in bacteriophage-based therapeutics: Insight into the post-antibiotic era

H Ling, X Lou, Q Luo, Z He, M Sun, J Sun - Acta Pharmaceutica Sinica B, 2022 - Elsevier
Antibiotic resistance is one of the biggest threats to global health, as it can make the
treatment of bacterial infections in humans difficult owing to their high incidence rate …

[HTML][HTML] Genetic engineering of bacteriophages against infectious diseases

Y Chen, H Batra, J Dong, C Chen, VB Rao… - Frontiers in …, 2019 - frontiersin.org
Bacteriophages (phages) are the most abundant and widely distributed organisms on Earth,
constituting a virtually unlimited resource to explore the development of biomedical …

[HTML][HTML] The preclinical and clinical progress of bacteriophages and their lytic enzymes: the parts are easier than the whole

K Abdelkader, H Gerstmans, A Saafan, T Dishisha… - Viruses, 2019 - mdpi.com
The therapeutic potential of phages has been considered since their first identification more
than a century ago. The evident concept of using a natural predator to treat bacterial …

[HTML][HTML] Engineering therapeutic phages for enhanced antibacterial efficacy

S Meile, J Du, M Dunne, S Kilcher… - Current opinion in virology, 2022 - Elsevier
The alarming rise in antimicrobial resistance coupled with a lack of innovation in antibiotics
has renewed interest in the development of alternative therapies to combat bacterial …