Recent accomplishments on the synthetic/biological facets of pharmacologically active 1H-1, 2, 3-triazoles
The continuous demand of medicinally important scaffolds has prompted the synthetic
chemists to identify simple and efficient routes for their synthesis. 1H-1, 2, 3-triazole …
chemists to identify simple and efficient routes for their synthesis. 1H-1, 2, 3-triazole …
Current strategies in development of new chromone derivatives with diversified pharmacological activities: A review
NA Mohsin, M Irfan, S Hassan, U Saleem - Pharmaceutical chemistry …, 2020 - Springer
Chromone derivatives possess a spectrum of biological activities. Chromone has been
recognized as a privileged structure for new drug invention and development. Substitution …
recognized as a privileged structure for new drug invention and development. Substitution …
Chromone, a privileged scaffold in drug discovery: Developments in the synthesis and bioactivity
AT Benny, SD Arikkatt, CG Vazhappilly… - Mini Reviews in …, 2022 - ingentaconnect.com
Chromones are the class of secondary metabolites that broadly occur in the plant kingdom
in a noticeable quantity. This rigid bicyclic system has been categorized “as privileged …
in a noticeable quantity. This rigid bicyclic system has been categorized “as privileged …
Design, synthesis and antitubercular assessment of 1, 2, 3-triazole incorporated thiazolylcarboxylate derivatives
Abstract A library of 1, 2, 3-triazole incorporated thiazolylcarboxylate derivatives (7a-q) and
(8a-j) were synthesized and evaluated for their in-vitro antitubercular activity against …
(8a-j) were synthesized and evaluated for their in-vitro antitubercular activity against …
Novel isoniazid embedded triazole derivatives: Synthesis, antitubercular and antimicrobial activity evaluation
PS Patil, SL Kasare, NB Haval, VM Khedkar… - Bioorganic & medicinal …, 2020 - Elsevier
In the present study, a series of new isoniazid embedded triazole derivatives have been
synthesized. These compounds were evaluated for their in vitro antitubercular and …
synthesized. These compounds were evaluated for their in vitro antitubercular and …
Design and synthesis of new indanol-1, 2, 3-triazole derivatives as potent antitubercular and antimicrobial agents
PS Phatak, RD Bakale, RS Kulkarni, ST Dhumal… - Bioorganic & Medicinal …, 2020 - Elsevier
In a search of new antitubercular agents, herein we have reported a series of new thirty-two
indanol-1, 2, 3-triazole derivatives. The synthesized compounds were screened for their in …
indanol-1, 2, 3-triazole derivatives. The synthesized compounds were screened for their in …
Synthesis of heterocyclic analogs of isoflavone and homoisoflavone based on 3-formylchromone
SS Shatokhin, VA Tuskaev, SC Gagieva… - Russian Chemical …, 2021 - Springer
The review is focused on recent developments of chemistry of synthetic analogs of natural
compounds, isoflavone and homoisoflavone. The possible synthetic strategies to access …
compounds, isoflavone and homoisoflavone. The possible synthetic strategies to access …
[HTML][HTML] Thiazole, triazole, thio-and semicarbazone derivatives-Promising moieties for drug development for the treatment of tuberculosis
Thiazole, triazole, thio and semicarbazones are privileged motifs that act as
pharmacophores in bioactive compounds for various diseases, such as Tuberculosis (TB) …
pharmacophores in bioactive compounds for various diseases, such as Tuberculosis (TB) …
Accessing α-Arylated Nitriles via BF3·OEt2 Catalyzed Cyanation of para-Quinone Methides Using tert-Butyl Isocyanide as a Cyanide Source
BF3· OEt2 catalyzed 1, 6-conjugate addition of tert-butyl isocyanide to para-quinone
methides and fuchsones for the synthesis of α-diaryl and α-triaryl nitriles has been reported …
methides and fuchsones for the synthesis of α-diaryl and α-triaryl nitriles has been reported …
The first-in-class pyrazole-based dual InhA-VEGFR inhibitors towards integrated antitubercular host-directed therapy
Several facets of the host response to tuberculosis have been tapped for clinical
investigation, especially targeting angiogenesis mediated by VEGF signaling from infected …
investigation, especially targeting angiogenesis mediated by VEGF signaling from infected …