Noradrenergic ensemble-based modulation of cognition over multiple timescales

NKB Totah, NK Logothetis, O Eschenko - Brain research, 2019 - Elsevier
Cognition fluctuates over relatively faster and slower timescales. This is enabled by dynamic
interactions among cortical neurons over similarly diverse temporal and spatial scales. Fast …

Tyrosine hydroxylase as a sentinel for central and peripheral tissue responses in Parkinson's progression: Evidence from clinical studies and neurotoxin models

ME Johnson, MF Salvatore, SA Maiolo… - Progress in …, 2018 - Elsevier
Parkinson's disease (PD) is a common neurodegenerative disease worldwide. While the
typical motor symptoms of PD are well known, the lesser known non-motor symptoms can …

Olfactory neurogenesis plays different parts at successive stages of life, implications for mental health

J Dejou, N Mandairon, A Didier - Frontiers in Neural Circuits, 2024 - frontiersin.org
The olfactory bulb is a unique site of continuous neurogenesis, primarily generating
inhibitory interneurons, a process that begins at birth and extends through infancy and …

The role of the stimulus in olfactory plasticity

DM Coppola, J Reisert - Brain Sciences, 2023 - mdpi.com
Plasticity, the term we use to describe the ability of a nervous system to change with
experience, is the evolutionary adaptation that freed animal behavior from the confines of …

Changes in olfactory sensory neuron physiology and olfactory perceptual learning after odorant exposure in adult mice

MD Kass, SA Guang, AH Moberly… - Chemical senses, 2016 - academic.oup.com
The adult olfactory system undergoes experience-dependent plasticity to adapt to the
olfactory environment. This plasticity may be accompanied by perceptual changes, including …

Comparative study of chemical neuroanatomy of the olfactory neuropil in mouse, honey bee, and human

I Sinakevitch, GR Bjorklund, JM Newbern… - Biological …, 2018 - Springer
Despite divergent evolutionary origins, the organization of olfactory systems is remarkably
similar across phyla. In both insects and mammals, sensory input from receptor cells is …

The effect of odor enrichment on olfactory acuity: Olfactometric testing in mice using two mirror-molecular pairs

A Blount, DM Coppola - PLoS One, 2020 - journals.plos.org
Intelligent systems in nature like the mammalian nervous system benefit from adaptable
inputs that can tailor response profiles to their environment that varies in time and space …

[HTML][HTML] Long-term olfactory enrichment promotes non-olfactory cognition, noradrenergic plasticity and remodeling of brain functional connectivity in older mice

C Terrier, J Greco-Vuilloud, M Cavelius, M Thévenet… - Neurobiology of …, 2024 - Elsevier
Brain functional and structural changes lead to cognitive decline during aging, but a high
level of cognitive stimulation during life can improve cognitive performances in the older …

Intranasal administration of sodium dimethyldithiocarbamate induces motor deficits and dopaminergic dysfunction in mice

JM Mack, TM Moura, D Lanznaster, F Bobinski… - Neurotoxicology, 2018 - Elsevier
The primary etiology of Parkinson's disease (PD) remains unclear, but likely reflects a
combination of genetic and environmental factors. Exposure to some pesticides, including …

12 months is a pivotal age for olfactory perceptual learning and its underlying neuronal plasticity in aging mice

J Greco-Vuilloud, M Midroit, C Terrier, J Forest… - Neurobiology of …, 2022 - Elsevier
Normal brain aging is associated with deficits in cognitive and sensory processes, due to
subtle impairment of synaptic contacts and plasticity. Impairment may be discrete in basal …