The secretion profile of mesenchymal stem cells and potential applications in treating human diseases
Y Han, J Yang, J Fang, Y Zhou, E Candi… - … and Targeted Therapy, 2022 - nature.com
Mesenchymal stromal/stem cells (MSCs) possess multi-lineage differentiation and self-
renewal potentials. MSCs-based therapies have been widely utilized for the treatment of …
renewal potentials. MSCs-based therapies have been widely utilized for the treatment of …
Melatonin and inflammation—Story of a double‐edged blade
R Hardeland - Journal of pineal research, 2018 - Wiley Online Library
Melatonin is an immune modulator that displays both pro‐and anti‐inflammatory properties.
Proinflammatory actions, which are well documented by many studies in isolated cells or …
Proinflammatory actions, which are well documented by many studies in isolated cells or …
Melatonin enhances osteogenic differentiation of dental pulp mesenchymal stem cells by regulating MAPK pathways and promotes the efficiency of bone regeneration …
YH Chan, KN Ho, YC Lee, MJ Chou, WZ Lew… - Stem Cell Research & …, 2022 - Springer
Background Mesenchymal stem cell (MSC)-based tissue engineering plays a major role in
regenerative medicine. However, the efficiency of MSC transplantation and survival of …
regenerative medicine. However, the efficiency of MSC transplantation and survival of …
Protective role of melatonin in cardiac ischemia‐reperfusion injury: From pathogenesis to targeted therapy
Acute myocardial infarction (MI) is a major cause of mortality and disability worldwide. In
patients with MI, the treatment option for reducing acute myocardial ischemic injury and …
patients with MI, the treatment option for reducing acute myocardial ischemic injury and …
Melatonin: A novel candidate for the treatment of osteoarthritis
Y Zhang, T Liu, H Yang, F He, X Zhu - Ageing research reviews, 2022 - Elsevier
Osteoarthritis (OA), characterized by cartilage erosion, synovium inflammation, and
subchondral bone remodeling, is a common joint degenerative disease worldwide. OA …
subchondral bone remodeling, is a common joint degenerative disease worldwide. OA …
Melatonin effects on bone: implications for use as a therapy for managing bone loss
F Munmun, PA Witt‐Enderby - Journal of pineal research, 2021 - Wiley Online Library
Melatonin is the primary circadian output signal from the brain and is mainly synthesized in
pinealocytes. The rhythm and secretion of melatonin are under the control of an …
pinealocytes. The rhythm and secretion of melatonin are under the control of an …
Fundamental issues related to the origin of melatonin and melatonin isomers during evolution: relation to their biological functions
DX Tan, X Zheng, J Kong, LC Manchester… - International Journal of …, 2014 - mdpi.com
Melatonin and melatonin isomers exist and/or coexist in living organisms including yeasts,
bacteria and plants. The levels of melatonin isomers are significantly higher than that of …
bacteria and plants. The levels of melatonin isomers are significantly higher than that of …
Injectable PNIPAM/Hyaluronic acid hydrogels containing multipurpose modified particles for cartilage tissue engineering: Synthesis, characterization, drug release …
Novel injectable thermosensitive PNIPAM/hyaluronic acid hydrogels containing various
amounts of chitosan-g-acrylic acid coated PLGA (ACH-PLGA) micro/nanoparticles were …
amounts of chitosan-g-acrylic acid coated PLGA (ACH-PLGA) micro/nanoparticles were …
Coordinated regulation of melatonin synthesis and degradation genes in rice leaves in response to cadmium treatment
Y Byeon, HY Lee, OJ Hwang, HJ Lee… - Journal of Pineal …, 2015 - Wiley Online Library
We investigated the expression patterns of genes involved in melatonin synthesis and
degradation in rice leaves upon cadmium (Cd) treatment and the subcellular localization …
degradation in rice leaves upon cadmium (Cd) treatment and the subcellular localization …
Engineering approaches for effective therapeutic applications based on extracellular vesicles
The biological significance of extracellular vesicles (EVs) as intercellular communication
mediators has been increasingly revealed in a wide range of normal physiological …
mediators has been increasingly revealed in a wide range of normal physiological …