Adenosine is a key endogenous molecule that regulates tissue function by activating four G-
protein-coupled adenosine receptors: A1, A2A, A2B and A3. Cells of the immune system …

Background Vitamin D plays a role in several immune-mediated diseases, but its
association with inflammatory bowel disease (IBD) is unclear. We conducted a systematic …

The human body is colonized by a large number of microbes coexisting peacefully with their
host. The most colonized site is the gastrointestinal tract (GIT). More than 70% of all the …

Stevioside, an abundant component of Stevia rebaudiana leaf, has become well-known for
its intense sweetness (250–300 times sweeter than sucrose) and is used as a non-caloric …

Inflammatory bowel diseases (IBDs) are chronic ailments, Crohn's disease and ulcerative
colitis being the most important. These diseases present an inflammatory profile and they …

Objective The differential role of the IL-1 agonists, IL-1α, which is mainly cell-associated
versus IL-1β, which is mostly secreted, was studied in colon inflammation. Design Dextran …

Background: Vitamin D (VitD) deficiency is prevalent in patient with inflammatory bowel
disease (IBD). Recent studies have found that VitD can induce and maintain IBD remission …

A 2B adenosine receptors are increasingly recognized as important orchestrators of
inflammation. A 2B receptor activation promotes the inflammatory response of mast cells …

The SAMP1/YitFc mouse strain represents a model of Crohn's disease (CD)-like ileitis that is
ideal for investigating the pathogenesis of chronic intestinal inflammation. Different from the …

Curcumin is a naturally occurring nutraceutical compound with a number of therapeutic and
biological activities such as antioxidant, anti‐inflammatory, anti‐diabetic, antitumor, and …